Research output per year
Research output per year
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Dive into the research topics where Wade Van Horn is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Hinge-shift mechanism as a protein design principle for the evolution of β-lactamases from substrate promiscuity to specificity
Modi, T., Risso, V. A., Martinez-Rodriguez, S., Gavira, J. A., Mebrat, M. D., Van Horn, W. D., Sanchez-Ruiz, J. M. & Banu Ozkan, S., Dec 2021, In: Nature communications. 12, 1, 1852.Research output: Contribution to journal › Article › peer-review
Open Access -
Evidence that the TRPV1 S1-S4 membrane domain contributes to thermosensing
Kim, M., Sisco, N. J., Hilton, J. K., Montano, C. M., Castro, M. A., Cherry, B. R., Levitus, M. & Van Horn, W. D., Dec 1 2020, In: Nature communications. 11, 1, 4169.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Hyperthermia induced by transient receptor potential vanilloid-1 (TRPV1) antagonists in human clinical trials: Insights from mathematical modeling and meta-analysis
Garami, A., Shimansky, Y. P., Rumbus, Z., Vizin, R. C. L., Farkas, N., Hegyi, J., Szakacs, Z., Solymar, M., Csenkey, A., Chiche, D. A., Kapil, R., Kyle, D. J., Van Horn, W. D., Hegyi, P. & Romanovsky, A. A., Apr 2020, In: Pharmacology and Therapeutics. 208, 107474.Research output: Contribution to journal › Review article › peer-review
Open Access22 Scopus citations -
PIRT the TRP channel regulating protein binds calmodulin and cholesterol-like ligands
Sisco, N. J., Luu, D. D., Kim, M. & Van Horn, W. D., Mar 2020, In: Biomolecules. 10, 3, 478.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Structure-Based Design of Novel Biphenyl Amide Antagonists of Human Transient Receptor Potential Cation Channel Subfamily M Member 8 Channels with Potential Implications in the Treatment of Sensory Neuropathies
Journigan, V. B., Feng, Z., Rahman, S., Wang, Y., Amin, A. R. M. R., Heffner, C. E., Bachtel, N., Wang, S., Gonzalez-Rodriguez, S., Fernández-Carvajal, A., Fernández-Ballester, G., Hilton, J. K., Van Horn, W. D., Ferrer-Montiel, A., Xie, X. Q. & Rahman, T., Feb 5 2020, In: ACS chemical neuroscience. 11, 3, p. 268-290 23 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations
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Collaborative Research: Role of DNA sequence and deformability on lesion recognit
National Science Foundation (NSF)
7/15/19 → 6/30/22
Project: Research project
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PIRT Family Modulation of TRPM8
HHS-NIH: National Institute of General Medical Sciences (NIGMS)
7/1/15 → 6/30/21
Project: Research project
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Center for Membrane Protein Drug Discovery (MEDD)
Fromme, P., Spence, J., Weierstall, U., Nannenga, B., Fromme, R., Wiktor, P., Kirian, R., Ros, A., Wang, S., LaBaer, J., Anderson, K., Qiu, J., Van Horn, W., Hansen, D., Sayres, S., Liu, W., Mills, J. & Graves, W.
HHS: National Institutes of Health (NIH)
4/1/16 → 8/30/20
Project: Research project
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MRI: Acquisition of Cryo-EM for Southwest Regional Center
Spence, J., Westerhoff, P., Vermaas, W., Frasch, W., Roberson, R., Carpenter, R., Rez, P., Weierstall, U., Muthuswamy, J., Leket-Mor, T., Fromme, P., Hogue, B., Stabenfeldt, S., Mason, H., Yan, H., Rittmann, B., Torres, C., Wiktor, P., Rege, K., Halden, R., Ros, R., Ros, A., LaBaer, J., Olive, M., Liu, J., Van Horn, W. & Liu, W.
NSF-BIO: Division of Biological Infrastructure (DBI)
9/1/15 → 8/31/18
Project: Research project