Research Output per year
Fingerprint Dive into the research topics where Wade Van Horn is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
Micelles
Chemical Compounds
Magnetic Resonance Spectroscopy
Medicine & Life Sciences
Vitamin K Epoxide Reductases
Medicine & Life Sciences
Membrane Proteins
Medicine & Life Sciences
Nuclear magnetic resonance
Chemical Compounds
KCNQ1 Potassium Channel
Medicine & Life Sciences
Proteins
Medicine & Life Sciences
Ion Channels
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Research Output 2005 2019
Competitive Interactions between PIRT, the Cold Sensing Ion Channel TRPM8, and PIP2 Suggest a Mechanism for Regulation
Sisco, N. J., Helsell, C. V. M. & Van Horn, W. D., Dec 1 2019, In : Scientific reports. 9, 1, 14128.Research output: Contribution to journal › Article
Open Access
Phosphatidylinositols
Ion Channels
Magnetic Resonance Spectroscopy
Transient Receptor Potential Channels
Membrane Proteins
Structural and Evolutionary Insights Point to Allosteric Regulation of TRP Ion Channels
Hilton, J. K., Kim, M. & Van Horn, W., Jun 18 2019, In : Accounts of chemical research. 52, 6, p. 1643-1652 10 p.Research output: Contribution to journal › Article
Transient Receptor Potential Channels
Ion Channels
Ligands
Mints
Cloning
3
Citations
(Scopus)
Phosphoinositide-interacting regulator of TRP (PIRT) has opposing effects on human and mouse TRPM8 ion channels
Hilton, J. K., Salehpour, T., Sisco, N. J., Rath, P. & Van Horn, W., Jan 1 2018, In : Journal of Biological Chemistry. 293, 24, p. 9423-9434 12 p.Research output: Contribution to journal › Article
Phosphatidylinositols
Ion Channels
Modulation
Electrophysiology
Molecular Probes
4
Citations
(Scopus)
A parallel stranded G-quadruplex composed of threose nucleic acid (TNA)
Liao, J. Y., Anosova, I., Bala, S., Van Horn, W. & Chaput, J. C., Mar 1 2017, In : Biopolymers. 107, 3, e22999.Research output: Contribution to journal › Article
G-Quadruplexes
Nucleic acids
Nucleic Acids
DNA
Polymers
New pieces to an old puzzle: Identifying the warfarin-binding site that prevents clotting
Hilton, J. K. & Van Horn, W., Jan 5 2017, In : Nature Structural and Molecular Biology. 24, 1, p. 5-6 2 p.Research output: Contribution to journal › Comment/debate
Vitamin K Epoxide Reductases
Protein Conformation
Molecular Models
Blood Coagulation
Warfarin
Projects 2012 2020
PIRT Family Modulation of TRPM8
HHS-NIH: National Institute of General Medical Sciences (NIGMS)
7/1/15 → 6/30/20
Project: Research project
Center for Membrane Protein Drug Discovery (MEDD)
Fromme, P., Tao, N., Spence, J., Weierstall, U., Nannenga, B., Fromme, R., Wiktor, P., Kirian, R., Ros, A., Wang, S., LaBaer, J., Anderson, K., Qiu, J., Van Horn, W., Hansen, D., Sayres, S., Liu, W., Mills, J. & Graves, W.
National Institute for Health Care Management (NIHCM)
4/1/16 → 8/30/19
Project: Research project
Nanocrystals
Membrane Proteins
Peptides
Crystallization
Substrates
MRI: Acquisition of Cryo-EM for Southwest Regional Center
Spence, J., Westerhoff, P., Vermaas, W., Frasch, W., Roberson, R., Carpenter, R., Rez, P., Weierstall, U., Muthuswamy, J., Leket-Mor, T., Wachter, R., Fromme, P., Hogue, B., Stabenfeldt, S., Mason, H., Yan, H., Rittmann, B., Torres, C., Wiktor, P., Rege, K., Halden, R., Ros, R., Ros, A., LaBaer, J., Olive, M., Liu, J., Van Horn, W. & Liu, W.
NSF-BIO: Division of Biological Infrastructure (DBI)
9/1/15 → 8/31/18
Project: Research project
Cryoelectron Microscopy
Electrons
Proteins
Electron Microscopy
Scanning Transmission Electron Microscopy
The Emergence of Protein Folds
NASA: Goddard Space Flight Center
6/10/14 → 9/30/15
Project: Research project
Proteins
Earth (planet)
Molecules
Rapid Synthesis And Evolution Of Artificial TNA Polymers Having Affinity And Catalytic Activity
US Department of Defense (DOD)
6/1/14 → 8/31/17
Project: Research project