Wade Van Horn

Associate Professor

Associate Professor, Biodesign: Personalized Diagnostics, Virginia G. Piper Center for (PD)
Assistant Professor, CLAS-NS: Molecular Sciences, School of (SMS)

Source: Scopus
Calculated based on no. of publications stored in Pure and citations from Scopus

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1209 Citations
18 h-Index
25 Article
5 Review article
2 Comment/debate
2 Patent

Hyperthermia induced by transient receptor potential vanilloid-1 (TRPV1) antagonists in human clinical trials: Insights from mathematical modeling and meta-analysis
Garami, A., Shimansky, Y. P., Rumbus, Z., Vizin, R. C. L., Farkas, N., Hegyi, J., Szakacs, Z., Solymar, M., Csenkey, A., Chiche, D. A., Kapil, R., Kyle, D. J., Van Horn, W. D., Hegyi, P. & Romanovsky, A. A., Apr 2020, In: Pharmacology and Therapeutics. 208, 107474.
Research output: Contribution to journal › Review article › peer-review

Open Access
12 Scopus citations
PIRT the TRP channel regulating protein binds calmodulin and cholesterol-like ligands
Sisco, N. J., Luu, D. D., Kim, M. & Van Horn, W. D., Mar 2020, In: Biomolecules. 10, 3, 478.
Research output: Contribution to journal › Article › peer-review

Open Access
1 Scopus citations
Structure-Based Design of Novel Biphenyl Amide Antagonists of Human Transient Receptor Potential Cation Channel Subfamily M Member 8 Channels with Potential Implications in the Treatment of Sensory Neuropathies
Journigan, V. B., Feng, Z., Rahman, S., Wang, Y., Amin, A. R. M. R., Heffner, C. E., Bachtel, N., Wang, S., Gonzalez-Rodriguez, S., Fernández-Carvajal, A., Fernández-Ballester, G., Hilton, J. K., Van Horn, W. D., Ferrer-Montiel, A., Xie, X. Q. & Rahman, T., Feb 5 2020, In: ACS chemical neuroscience. 11, 3, p. 268-290 23 p.
Research output: Contribution to journal › Article › peer-review
5 Scopus citations
Competitive Interactions between PIRT, the Cold Sensing Ion Channel TRPM8, and PIP₂ Suggest a Mechanism for Regulation
Sisco, N. J., Helsell, C. V. M. & Van Horn, W. D., Dec 1 2019, In: Scientific reports. 9, 1, 14128.
Research output: Contribution to journal › Article › peer-review

Open Access
3 Scopus citations
Structural and Evolutionary Insights Point to Allosteric Regulation of TRP Ion Channels
Hilton, J. K., Kim, M. & Van Horn, W., Jun 18 2019, In: Accounts of chemical research. 52, 6, p. 1643-1652 10 p.
Research output: Contribution to journal › Article › peer-review
7 Scopus citations

2 Active
6 Finished

Collaborative Research: Role of DNA sequence and deformability on lesion recognition and excision in the base excision repair pathway
Levitus, M. & Van Horn, W.
National Science Foundation (NSF)
7/15/19 → 6/30/22
Project: Research project
PIRT Family Modulation of TRPM8
Van Horn, W.
HHS-NIH: National Institute of General Medical Sciences (NIGMS)
7/1/15 → 6/30/21
Project: Research project
RubrYc Therapeutics, Inc. SRA
Van Horn, W.
INDUSTRY: Domestic Company
10/1/20 → 10/31/20
Project: Research project
Center for Membrane Protein Drug Discovery (MEDD)
Fromme, P., Spence, J., Weierstall, U., Nannenga, B., Fromme, R., Wiktor, P., Kirian, R., Ros, A., Wang, S., LaBaer, J., Anderson, K., Qiu, J., Van Horn, W., Hansen, D., Sayres, S., Liu, W., Mills, J. & Graves, W.
HHS: National Institutes of Health (NIH)
4/1/16 → 8/30/20
Project: Research project
MRI: Acquisition of Cryo-EM for Southwest Regional Center
Spence, J., Westerhoff, P., Vermaas, W., Frasch, W., Roberson, R., Carpenter, R., Rez, P., Weierstall, U., Muthuswamy, J., Leket-Mor, T., Fromme, P., Hogue, B., Stabenfeldt, S., Mason, H., Yan, H., Rittmann, B., Torres, C., Wiktor, P., Rege, K., Halden, R., Ros, R., Ros, A., LaBaer, J., Olive, M., Liu, J., Van Horn, W. & Liu, W.
NSF-BIO: Division of Biological Infrastructure (DBI)
9/1/15 → 8/31/18
Project: Research project