TY - GEN
T1 - Transform-domain features for ion-channel sensors
AU - Kwon, Homin
AU - Knee, Peter
AU - Spanias, Andreas
AU - Goodnick, Stephen
AU - Thornton, Trevor
AU - Phillips, Stephen
PY - 2008
Y1 - 2008
N2 - An ion-channel platform can be used for stochastic sensing at the molecule level. Digital signal processing techniques can be applied for detection, classification, and de-noising of ion-channel signals. In this paper, we present feature extraction and classification techniques for the analysis of the stochastic response of porin OmpF and α-hemolysin to several different analytes. In particular, we examine unitary transform representations of ionchannel currents. We study two transforms, namely, the Fourier transform and the Walsh transform. Preliminary results using a Hidden Markov model classifier are presented.
AB - An ion-channel platform can be used for stochastic sensing at the molecule level. Digital signal processing techniques can be applied for detection, classification, and de-noising of ion-channel signals. In this paper, we present feature extraction and classification techniques for the analysis of the stochastic response of porin OmpF and α-hemolysin to several different analytes. In particular, we examine unitary transform representations of ionchannel currents. We study two transforms, namely, the Fourier transform and the Walsh transform. Preliminary results using a Hidden Markov model classifier are presented.
KW - DSP
KW - Feature extraction and classification
KW - Ion-channel sensors
KW - Walsh transform
UR - http://www.scopus.com/inward/record.url?scp=62949177952&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=62949177952&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:62949177952
SN - 9780889867178
T3 - Proceedings of the 5th IASTED International Conference on Signal Processing, Pattern Recognition, and Applications, SPPRA 2008
SP - 272
EP - 275
BT - Proceedings of the 5th IASTED International Conference on Signal Processing, Pattern Recognition, and Applications, SPPRA 2008
T2 - 5th IASTED International Conference on Signal Processing, Pattern Recognition, and Applications, SPPRA 2008
Y2 - 13 February 2008 through 15 February 2008
ER -