The sonographic diagnosis of acute gangrenous cholecystitis: Importance of the Murphy sign

J. F. Simeone, J. A. Brink, P. R. Mueller, C. Compton, P. F. Hahn, S. Saini, S. G. Silverman, G. Tung, J. T. Ferrucci

Research output: Contribution to journalArticle

64 Scopus citations

Abstract

The sonographic Murphy sign is defined as the presence of maximal tenderness elicited by direct pressure of the transducer over a sonographically localized gallbladder. The reported prevalence of this sign is more than 95% in patients with acute cholecystitis. In this series of 18 patients with pathologically proved gangrenous cholecystitis, the sonographic Murphy sign was positive in only six (33%). Clinical examination showed a positive Murphy sign in eight patients (44%), diffuse abdominal pain in nine patients (50%), and no pain in one patient (6%). Other sonographic findings included pericholecystic fluid (10), thickening of the gallbladder wall (10), and a dilated gallbladder (five). Our experience suggests that the absence of the Murphy sign increases the possibility of gangrenous cholecystitis in patients with abdominal pain and sonographic findings of cholecystitis.

Original languageEnglish (US)
Pages (from-to)289-290
Number of pages2
JournalAmerican Journal of Roentgenology
Volume152
Issue number2
DOIs
StatePublished - Jan 1 1989
Externally publishedYes

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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    Simeone, J. F., Brink, J. A., Mueller, P. R., Compton, C., Hahn, P. F., Saini, S., Silverman, S. G., Tung, G., & Ferrucci, J. T. (1989). The sonographic diagnosis of acute gangrenous cholecystitis: Importance of the Murphy sign. American Journal of Roentgenology, 152(2), 289-290. https://doi.org/10.2214/ajr.152.2.289