The evolvability of lead peptides from small library screens

Jinglei Zhang, Berea A R Williams, Mikael T. Nilsson, John C. Chaput

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Very little is known about the evolvability of lead peptides that are isolated from small library screens. Here we begin to explore this question by comparing the directed evolution of two peptides previously isolated from a small library screen to new ligands generated de novo by in vitro selection.

Original languageEnglish (US)
Pages (from-to)7778-7780
Number of pages3
JournalChemical Communications
Volume46
Issue number41
DOIs
StatePublished - Nov 7 2010

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Peptides
Lead
Ligands

ASJC Scopus subject areas

  • Metals and Alloys
  • Materials Chemistry
  • Surfaces, Coatings and Films
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Catalysis
  • Chemistry(all)

Cite this

Zhang, J., Williams, B. A. R., Nilsson, M. T., & Chaput, J. C. (2010). The evolvability of lead peptides from small library screens. Chemical Communications, 46(41), 7778-7780. https://doi.org/10.1039/c0cc01475c

The evolvability of lead peptides from small library screens. / Zhang, Jinglei; Williams, Berea A R; Nilsson, Mikael T.; Chaput, John C.

In: Chemical Communications, Vol. 46, No. 41, 07.11.2010, p. 7778-7780.

Research output: Contribution to journalArticle

Zhang, J, Williams, BAR, Nilsson, MT & Chaput, JC 2010, 'The evolvability of lead peptides from small library screens', Chemical Communications, vol. 46, no. 41, pp. 7778-7780. https://doi.org/10.1039/c0cc01475c
Zhang J, Williams BAR, Nilsson MT, Chaput JC. The evolvability of lead peptides from small library screens. Chemical Communications. 2010 Nov 7;46(41):7778-7780. https://doi.org/10.1039/c0cc01475c
Zhang, Jinglei ; Williams, Berea A R ; Nilsson, Mikael T. ; Chaput, John C. / The evolvability of lead peptides from small library screens. In: Chemical Communications. 2010 ; Vol. 46, No. 41. pp. 7778-7780.
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