The Ancient Evolutionary History of Polyomaviruses

Christopher B. Buck; Koenraad Van Doorslaer; Alberto Peretti; Eileen M. Geoghegan; Michael J. Tisza; Ping An; Joshua P. Katz; James M. Pipas; Alison A. McBride; Alvin C. Camus; Alexa J. McDermott; Jennifer A. Dill; Eric Delwart; Terry F.F. Ng; Kata Farkas; Charlotte Austin; Simona Kraberger; William Davison; Diana V. Pastrana; Arvind Varsani

doi:10.1371/journal.ppat.1005574

The Ancient Evolutionary History of Polyomaviruses

Christopher B. Buck, Koenraad Van Doorslaer, Alberto Peretti, Eileen M. Geoghegan, Michael J. Tisza, Ping An, Joshua P. Katz, James M. Pipas, Alison A. McBride, Alvin C. Camus, Alexa J. McDermott, Jennifer A. Dill, Eric Delwart, Terry F.F. Ng, Kata Farkas, Charlotte Austin, Simona Kraberger, William Davison, Diana V. Pastrana, Arvind Varsani

Research output: Contribution to journal › Article › peer-review

136 Scopus citations

Abstract

Polyomaviruses are a family of DNA tumor viruses that are known to infect mammals and birds. To investigate the deeper evolutionary history of the family, we used a combination of viral metagenomics, bioinformatics, and structural modeling approaches to identify and characterize polyomavirus sequences associated with fish and arthropods. Analyses drawing upon the divergent new sequences indicate that polyomaviruses have been gradually co-evolving with their animal hosts for at least half a billion years. Phylogenetic analyses of individual polyomavirus genes suggest that some modern polyomavirus species arose after ancient recombination events involving distantly related polyomavirus lineages. The improved evolutionary model provides a useful platform for developing a more accurate taxonomic classification system for the viral family Polyomaviridae.

Original language	English (US)
Article number	e1005574
Journal	PLoS Pathogens
Volume	12
Issue number	4
DOIs	https://doi.org/10.1371/journal.ppat.1005574
State	Published - Apr 2016
Externally published	Yes

ASJC Scopus subject areas

Parasitology
Microbiology
Immunology
Molecular Biology
Genetics
Virology

Access to Document

10.1371/journal.ppat.1005574

Cite this

Buck, C. B., Van Doorslaer, K., Peretti, A., Geoghegan, E. M., Tisza, M. J., An, P., Katz, J. P., Pipas, J. M., McBride, A. A., Camus, A. C., McDermott, A. J., Dill, J. A., Delwart, E., Ng, T. F. F., Farkas, K., Austin, C., Kraberger, S., Davison, W., Pastrana, D. V., & Varsani, A. (2016). The Ancient Evolutionary History of Polyomaviruses. PLoS Pathogens, 12(4), Article e1005574. https://doi.org/10.1371/journal.ppat.1005574

Buck, CB, Van Doorslaer, K, Peretti, A, Geoghegan, EM, Tisza, MJ, An, P, Katz, JP, Pipas, JM, McBride, AA, Camus, AC, McDermott, AJ, Dill, JA, Delwart, E, Ng, TFF, Farkas, K, Austin, C, Kraberger, S, Davison, W, Pastrana, DV & Varsani, A 2016, 'The Ancient Evolutionary History of Polyomaviruses', PLoS Pathogens, vol. 12, no. 4, e1005574. https://doi.org/10.1371/journal.ppat.1005574

@article{75e42bc0f782498a844b2fd6cdac9681,

title = "The Ancient Evolutionary History of Polyomaviruses",

abstract = "Polyomaviruses are a family of DNA tumor viruses that are known to infect mammals and birds. To investigate the deeper evolutionary history of the family, we used a combination of viral metagenomics, bioinformatics, and structural modeling approaches to identify and characterize polyomavirus sequences associated with fish and arthropods. Analyses drawing upon the divergent new sequences indicate that polyomaviruses have been gradually co-evolving with their animal hosts for at least half a billion years. Phylogenetic analyses of individual polyomavirus genes suggest that some modern polyomavirus species arose after ancient recombination events involving distantly related polyomavirus lineages. The improved evolutionary model provides a useful platform for developing a more accurate taxonomic classification system for the viral family Polyomaviridae.",

author = "Buck, {Christopher B.} and {Van Doorslaer}, Koenraad and Alberto Peretti and Geoghegan, {Eileen M.} and Tisza, {Michael J.} and Ping An and Katz, {Joshua P.} and Pipas, {James M.} and McBride, {Alison A.} and Camus, {Alvin C.} and McDermott, {Alexa J.} and Dill, {Jennifer A.} and Eric Delwart and Ng, {Terry F.F.} and Kata Farkas and Charlotte Austin and Simona Kraberger and William Davison and Pastrana, {Diana V.} and Arvind Varsani",

year = "2016",

month = apr,

doi = "10.1371/journal.ppat.1005574",

language = "English (US)",

volume = "12",

journal = "PLoS Pathogens",

issn = "1553-7366",

publisher = "Public Library of Science",

number = "4",

}

TY - JOUR

T1 - The Ancient Evolutionary History of Polyomaviruses

AU - Buck, Christopher B.

AU - Van Doorslaer, Koenraad

AU - Peretti, Alberto

AU - Geoghegan, Eileen M.

AU - Tisza, Michael J.

AU - An, Ping

AU - Katz, Joshua P.

AU - Pipas, James M.

AU - McBride, Alison A.

AU - Camus, Alvin C.

AU - McDermott, Alexa J.

AU - Dill, Jennifer A.

AU - Delwart, Eric

AU - Ng, Terry F.F.

AU - Farkas, Kata

AU - Austin, Charlotte

AU - Kraberger, Simona

AU - Davison, William

AU - Pastrana, Diana V.

AU - Varsani, Arvind

PY - 2016/4

Y1 - 2016/4

N2 - Polyomaviruses are a family of DNA tumor viruses that are known to infect mammals and birds. To investigate the deeper evolutionary history of the family, we used a combination of viral metagenomics, bioinformatics, and structural modeling approaches to identify and characterize polyomavirus sequences associated with fish and arthropods. Analyses drawing upon the divergent new sequences indicate that polyomaviruses have been gradually co-evolving with their animal hosts for at least half a billion years. Phylogenetic analyses of individual polyomavirus genes suggest that some modern polyomavirus species arose after ancient recombination events involving distantly related polyomavirus lineages. The improved evolutionary model provides a useful platform for developing a more accurate taxonomic classification system for the viral family Polyomaviridae.

AB - Polyomaviruses are a family of DNA tumor viruses that are known to infect mammals and birds. To investigate the deeper evolutionary history of the family, we used a combination of viral metagenomics, bioinformatics, and structural modeling approaches to identify and characterize polyomavirus sequences associated with fish and arthropods. Analyses drawing upon the divergent new sequences indicate that polyomaviruses have been gradually co-evolving with their animal hosts for at least half a billion years. Phylogenetic analyses of individual polyomavirus genes suggest that some modern polyomavirus species arose after ancient recombination events involving distantly related polyomavirus lineages. The improved evolutionary model provides a useful platform for developing a more accurate taxonomic classification system for the viral family Polyomaviridae.

UR - http://www.scopus.com/inward/record.url?scp=84964812248&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84964812248&partnerID=8YFLogxK

U2 - 10.1371/journal.ppat.1005574

DO - 10.1371/journal.ppat.1005574

M3 - Article

C2 - 27093155

AN - SCOPUS:84964812248

SN - 1553-7366

VL - 12

JO - PLoS Pathogens

JF - PLoS Pathogens

IS - 4

M1 - e1005574

ER -

The Ancient Evolutionary History of Polyomaviruses

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this