SYNTHESIS IN PROCESS DEVELOPMENT.

George Stephanopoulos, D. W. Townsend

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Synthesis issues at the process development stage generate large combinatorial problems whose solution has a profound effect on the feasibility and optimality of the resulting processing schemes. This paper deals with the formulation of various such synthesis problems, examines their principal characteristics and how they scope the solution procedures. In particular, the paper addresses the following issues and methodologies: (1) How topological characteristics of the search space define patterns which can be exploited for the systematic generation of attractive chemical production schemes. (2) What characteristics define targeting procedures and evolutionary syntheses for the design of molecules with desired physical properties. (3) How knowledge-based expert systems can be designed for the design of molecules and the synthesis of feasible and attractive biochemical pathways.

Original languageEnglish (US)
Pages (from-to)160-174
Number of pages15
JournalChemical Engineering Research and Design
Volume64
Issue number3
StatePublished - May 1 1986
Externally publishedYes

Fingerprint

Molecules
Expert systems
Physical properties
Processing

ASJC Scopus subject areas

  • Polymers and Plastics

Cite this

SYNTHESIS IN PROCESS DEVELOPMENT. / Stephanopoulos, George; Townsend, D. W.

In: Chemical Engineering Research and Design, Vol. 64, No. 3, 01.05.1986, p. 160-174.

Research output: Contribution to journalArticle

@article{176b4286b8524c70a9a5f6ea7ae8792e,
title = "SYNTHESIS IN PROCESS DEVELOPMENT.",
abstract = "Synthesis issues at the process development stage generate large combinatorial problems whose solution has a profound effect on the feasibility and optimality of the resulting processing schemes. This paper deals with the formulation of various such synthesis problems, examines their principal characteristics and how they scope the solution procedures. In particular, the paper addresses the following issues and methodologies: (1) How topological characteristics of the search space define patterns which can be exploited for the systematic generation of attractive chemical production schemes. (2) What characteristics define targeting procedures and evolutionary syntheses for the design of molecules with desired physical properties. (3) How knowledge-based expert systems can be designed for the design of molecules and the synthesis of feasible and attractive biochemical pathways.",
author = "George Stephanopoulos and Townsend, {D. W.}",
year = "1986",
month = "5",
day = "1",
language = "English (US)",
volume = "64",
pages = "160--174",
journal = "Chemical Engineering Research and Design",
issn = "0263-8762",
publisher = "Institution of Chemical Engineers",
number = "3",

}

TY - JOUR

T1 - SYNTHESIS IN PROCESS DEVELOPMENT.

AU - Stephanopoulos, George

AU - Townsend, D. W.

PY - 1986/5/1

Y1 - 1986/5/1

N2 - Synthesis issues at the process development stage generate large combinatorial problems whose solution has a profound effect on the feasibility and optimality of the resulting processing schemes. This paper deals with the formulation of various such synthesis problems, examines their principal characteristics and how they scope the solution procedures. In particular, the paper addresses the following issues and methodologies: (1) How topological characteristics of the search space define patterns which can be exploited for the systematic generation of attractive chemical production schemes. (2) What characteristics define targeting procedures and evolutionary syntheses for the design of molecules with desired physical properties. (3) How knowledge-based expert systems can be designed for the design of molecules and the synthesis of feasible and attractive biochemical pathways.

AB - Synthesis issues at the process development stage generate large combinatorial problems whose solution has a profound effect on the feasibility and optimality of the resulting processing schemes. This paper deals with the formulation of various such synthesis problems, examines their principal characteristics and how they scope the solution procedures. In particular, the paper addresses the following issues and methodologies: (1) How topological characteristics of the search space define patterns which can be exploited for the systematic generation of attractive chemical production schemes. (2) What characteristics define targeting procedures and evolutionary syntheses for the design of molecules with desired physical properties. (3) How knowledge-based expert systems can be designed for the design of molecules and the synthesis of feasible and attractive biochemical pathways.

UR - http://www.scopus.com/inward/record.url?scp=0022720970&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022720970&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0022720970

VL - 64

SP - 160

EP - 174

JO - Chemical Engineering Research and Design

JF - Chemical Engineering Research and Design

SN - 0263-8762

IS - 3

ER -