Synthesis and solution rheology of adenine-containing polyelectrolytes for electrospinning

Sean T. Hemp, Matthew T. Hunley, Shijing Cheng, Kerry C. Demella, Timothy E. Long

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Conventional free radical copolymerization of 9-vinylbenzyladenine (VBA) and 2-(dimethylamino)ethyl methacrylate (DMAEMA) with subsequent protonation afforded the synthesis of adenine-containing polyelectrolytes. All adenine-containing polyelectrolytes exhibited classical polyelectrolyte solution rheological behavior with scaling factors near 0.6 and 1.6 in the semidilute unentangled and semidilute entangled regimes, respectively. However, the adenine-containing polyelectrolytes deviated from polyelectrolyte behavior in the concentrated regime with increasing scaling factors as adenine-incorporation increased due to intermolecular association. The electrospinning behavior exhibited a strong dependence on adenine incorporation. Higher adenine-incorporation decreased the normalized concentration for fiber formation from 4.5Ce for PDMAEMA•HCl to 2.9Ce for 35 mol% VBA. The required zero-shear viscosities for electrospinning were 312 cP for PDMAEMA•HCl and 116 cP for the 35 mol% VBA copolymer. Increasing the adenine concentration also increased the fiber diameters presumably due to adenine-adenine interactions. These adenine-decorated electrospun mats exhibit potential in a variety of applications including filtration, purification, and tissue scaffolding.

Original languageEnglish (US)
Pages (from-to)1437-1443
Number of pages7
JournalPolymer
Volume53
Issue number7
DOIs
StatePublished - Mar 22 2012
Externally publishedYes

Keywords

  • Electrospinning
  • Nucleobases
  • Polyelectrolytes

ASJC Scopus subject areas

  • Organic Chemistry
  • Polymers and Plastics
  • Materials Chemistry

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