Studying mutation rate evolution in primates-the effects of computational pipelines and parameter choices

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Abstract

This commentary investigates the important role of computational pipeline and parameter choices in performing mutation rate estimation, using the recent article published in this journal by Bergeron et al. entitled "The germline mutational process in rhesus macaque and its implications for phylogenetic dating"as an illustrative example.

Original languageEnglish (US)
Article numbergiab069
JournalGigaScience
Volume10
Issue number10
DOIs
StatePublished - Oct 1 2021

Keywords

  • computational pipeline
  • de novo mutation
  • false-negative rate
  • false-positive rate
  • germline mutation rate
  • primates

ASJC Scopus subject areas

  • Health Informatics
  • Computer Science Applications

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