Abstract
The 30S ribosomal subunit binds messenger RNA and the anticodon stem- loop of transfer RNA during protein synthesis. A crystallographic analysis of the structure of the subunit from the bacterium Thermus thermophilus is presented. At a resolution of 5.5 Å, the phosphate backbone of the ribosomal RNA is visible, as are the α-helices of the ribosomal proteins, enabling double-helical regions of RNA to be identified throughout the subunit, all seven of the small-subunit proteins of known crystal structure to be positioned in the electron density map, and the fold of the entire central domain of the small-subunit ribosomal RNA to be determined.
Original language | English (US) |
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Pages (from-to) | 833-840 |
Number of pages | 8 |
Journal | Nature |
Volume | 400 |
Issue number | 6747 |
DOIs | |
State | Published - Aug 26 1999 |
Externally published | Yes |
ASJC Scopus subject areas
- General