Steroids and related natural products. Part XLI. 14α-Methyl Œstranes

George Pettit; Thomas H. Brown

doi:10.1039/J39670002024

Steroids and related natural products. Part XLI. 14α-Methyl Œstranes

George Pettit, Thomas H. Brown

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Œstrone has been converted into 14α-methylœstr-4-ene-3, 15-dione (V) in 14 steps. Direct alkylation at position 14 (activated by a 15-oxo-group) proved convenient for introducing the angular methyl group. Configuration of the 14-methyl substituent was established by o.r.d. measurements.

Original language	English (US)
Pages (from-to)	2024-2026
Number of pages	3
Journal	Journal of the Chemical Society C: Organic Chemistry
DOIs	https://doi.org/10.1039/J39670002024
State	Published - Dec 1 1967

ASJC Scopus subject areas

Organic Chemistry

Access to Document

10.1039/J39670002024

Fingerprint Dive into the research topics of 'Steroids and related natural products. Part XLI. 14α-Methyl Œstranes'. Together they form a unique fingerprint.

Cite this

@article{db79dfebd1bd48258d25ae6f0d3a733d,

title = "Steroids and related natural products. Part XLI. 14α-Methyl {\OE}stranes",

abstract = "{\OE}strone has been converted into 14α-methyl{\oe}str-4-ene-3, 15-dione (V) in 14 steps. Direct alkylation at position 14 (activated by a 15-oxo-group) proved convenient for introducing the angular methyl group. Configuration of the 14-methyl substituent was established by o.r.d. measurements.",

author = "George Pettit and Brown, {Thomas H.}",

year = "1967",

month = dec,

day = "1",

doi = "10.1039/J39670002024",

language = "English (US)",

pages = "2024--2026",

journal = "Journal of the Chemical Society C: Organic Chemistry",

issn = "0022-4952",

publisher = "Chemical Society",

}

TY - JOUR

T1 - Steroids and related natural products. Part XLI. 14α-Methyl Œstranes

AU - Pettit, George

AU - Brown, Thomas H.

PY - 1967/12/1

Y1 - 1967/12/1

N2 - Œstrone has been converted into 14α-methylœstr-4-ene-3, 15-dione (V) in 14 steps. Direct alkylation at position 14 (activated by a 15-oxo-group) proved convenient for introducing the angular methyl group. Configuration of the 14-methyl substituent was established by o.r.d. measurements.

AB - Œstrone has been converted into 14α-methylœstr-4-ene-3, 15-dione (V) in 14 steps. Direct alkylation at position 14 (activated by a 15-oxo-group) proved convenient for introducing the angular methyl group. Configuration of the 14-methyl substituent was established by o.r.d. measurements.

UR - http://www.scopus.com/inward/record.url?scp=37049116461&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=37049116461&partnerID=8YFLogxK

U2 - 10.1039/J39670002024

DO - 10.1039/J39670002024

M3 - Article

AN - SCOPUS:37049116461

SP - 2024

EP - 2026

JO - Journal of the Chemical Society C: Organic Chemistry

JF - Journal of the Chemical Society C: Organic Chemistry

SN - 0022-4952

ER -