Relations between mucosal immunity and children's mental health: The role of child sex

Peggy S. Keller; Mona El-Sheikh; Brian Vaughn; Douglas A. Granger

doi:10.1016/j.physbeh.2010.08.012

Relations between mucosal immunity and children's mental health: The role of child sex

Peggy S. Keller, Mona El-Sheikh, Brian Vaughn, Douglas A. Granger

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

Abstract

This study examines relations between children's salivary interleukin-6 (IL-6) and secretory immunoglobulin A (SIgA) and mental health. Child sex was considered as a moderator of relations. Data were from 329 normally developing children (M age = 9.85. years; SD = .98. years); 67% of children were European American and 33% were African American. Saliva samples were obtained during the afternoon and assayed for SIgA and IL-6. Parents completed questionnaire measures of child internalizing and externalizing symptoms, and children completed self-report measures of anxiety and depression. Structural equation models were fit to the data, and indicated that greater levels of salivary IL-6 and SIgA were associated with adjustment problems more strongly for girls than for boys.

Original language	English (US)
Pages (from-to)	705-712
Number of pages	8
Journal	Physiology and Behavior
Volume	101
Issue number	5
DOIs	https://doi.org/10.1016/j.physbeh.2010.08.012
State	Published - Dec 2 2010
Externally published	Yes

Keywords

Child mental health
Externalizing symptoms
Internalizing symptoms
Mucosal immunity
Salivary interleukin-6
Secretory immunoglobulin A
Sex differences

ASJC Scopus subject areas

Experimental and Cognitive Psychology
Behavioral Neuroscience

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10.1016/j.physbeh.2010.08.012

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abstract = "This study examines relations between children's salivary interleukin-6 (IL-6) and secretory immunoglobulin A (SIgA) and mental health. Child sex was considered as a moderator of relations. Data were from 329 normally developing children (M age = 9.85. years; SD = .98. years); 67% of children were European American and 33% were African American. Saliva samples were obtained during the afternoon and assayed for SIgA and IL-6. Parents completed questionnaire measures of child internalizing and externalizing symptoms, and children completed self-report measures of anxiety and depression. Structural equation models were fit to the data, and indicated that greater levels of salivary IL-6 and SIgA were associated with adjustment problems more strongly for girls than for boys.",

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AU - Keller, Peggy S.

AU - El-Sheikh, Mona

AU - Vaughn, Brian

AU - Granger, Douglas A.

PY - 2010/12/2

Y1 - 2010/12/2

N2 - This study examines relations between children's salivary interleukin-6 (IL-6) and secretory immunoglobulin A (SIgA) and mental health. Child sex was considered as a moderator of relations. Data were from 329 normally developing children (M age = 9.85. years; SD = .98. years); 67% of children were European American and 33% were African American. Saliva samples were obtained during the afternoon and assayed for SIgA and IL-6. Parents completed questionnaire measures of child internalizing and externalizing symptoms, and children completed self-report measures of anxiety and depression. Structural equation models were fit to the data, and indicated that greater levels of salivary IL-6 and SIgA were associated with adjustment problems more strongly for girls than for boys.

AB - This study examines relations between children's salivary interleukin-6 (IL-6) and secretory immunoglobulin A (SIgA) and mental health. Child sex was considered as a moderator of relations. Data were from 329 normally developing children (M age = 9.85. years; SD = .98. years); 67% of children were European American and 33% were African American. Saliva samples were obtained during the afternoon and assayed for SIgA and IL-6. Parents completed questionnaire measures of child internalizing and externalizing symptoms, and children completed self-report measures of anxiety and depression. Structural equation models were fit to the data, and indicated that greater levels of salivary IL-6 and SIgA were associated with adjustment problems more strongly for girls than for boys.

KW - Child mental health

KW - Externalizing symptoms

KW - Internalizing symptoms

KW - Mucosal immunity

KW - Salivary interleukin-6

KW - Secretory immunoglobulin A

KW - Sex differences

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Relations between mucosal immunity and children's mental health: The role of child sex

Abstract

Keywords

ASJC Scopus subject areas

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