Reconstructing the history of maize streak virus strain a dispersal to reveal diversification hot spots and its origin in southern Africa

Adérito L. Monjane, Gordon W. Harkins, Darren P. Martin, Philippe Lemey, Pierre Lefeuvre, Dionne N. Shepherd, Sunday Oluwafemi, Michelo Simuyandi, Innocent Zinga, Ephrem K. Komba, Didier P. Lakoutene, Noella Mandakombo, Joseph Mboukoulida, Silla Semballa, Appolinaire Tagne, Fidèle Tiendrébéogo, Julia B. Erdmann, Tania van Antwerpen, Betty E. Owor, Bradley Flett & 8 others Moses Ramusi, Oliver P. Windram, Rizwan Syed, Jean Michel Lett, Rob W. Briddon, Peter G. Markham, Edward P. Rybicki, Arvind Varsani

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

Maize streak virus strain A (MSV-A), the causal agent of maize streak disease, is today one of the most serious biotic threats to African food security. Determining where MSV-A originated and how it spread transcontinentally could yield valuable insights into its historical emergence as a crop pathogen. Similarly, determining where the major extant MSV-A lineages arose could identify geographical hot spots of MSV evolution. Here, we use model-based phylogeographic analyses of 353 fully sequenced MSV-A isolates to reconstruct a plausible history of MSV-A movements over the past 150 years. We show that since the probable emergence of MSV-A in southern Africa around 1863, the virus spread transcontinentally at an average rate of 32.5 km/year (95% highest probability density interval, 15.6 to 51.6 km/year). Using distinctive patterns of nucleotide variation caused by 20 unique intra-MSV-A recombination events, we tentatively classified the MSV-A isolates into 24 easily discernible lineages. Despite many of these lineages displaying distinct geographical distributions, it is apparent that almost all have emerged within the past 4 decades from either southern or east-central Africa. Collectively, our results suggest that regular analysis of MSV-A genomes within these diversification hot spots could be used to monitor the emergence of future MSV-A lineages that could affect maize cultivation in Africa.

Original languageEnglish (US)
Pages (from-to)9623-9636
Number of pages14
JournalJournal of Virology
Volume85
Issue number18
DOIs
StatePublished - Sep 2011
Externally publishedYes

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Maize streak virus
Southern Africa
History
history
Zea mays
Central Africa
Eastern Africa
corn
Food Supply
food security
Genetic Recombination

ASJC Scopus subject areas

  • Immunology
  • Virology

Cite this

Reconstructing the history of maize streak virus strain a dispersal to reveal diversification hot spots and its origin in southern Africa. / Monjane, Adérito L.; Harkins, Gordon W.; Martin, Darren P.; Lemey, Philippe; Lefeuvre, Pierre; Shepherd, Dionne N.; Oluwafemi, Sunday; Simuyandi, Michelo; Zinga, Innocent; Komba, Ephrem K.; Lakoutene, Didier P.; Mandakombo, Noella; Mboukoulida, Joseph; Semballa, Silla; Tagne, Appolinaire; Tiendrébéogo, Fidèle; Erdmann, Julia B.; van Antwerpen, Tania; Owor, Betty E.; Flett, Bradley; Ramusi, Moses; Windram, Oliver P.; Syed, Rizwan; Lett, Jean Michel; Briddon, Rob W.; Markham, Peter G.; Rybicki, Edward P.; Varsani, Arvind.

In: Journal of Virology, Vol. 85, No. 18, 09.2011, p. 9623-9636.

Research output: Contribution to journalArticle

Monjane, AL, Harkins, GW, Martin, DP, Lemey, P, Lefeuvre, P, Shepherd, DN, Oluwafemi, S, Simuyandi, M, Zinga, I, Komba, EK, Lakoutene, DP, Mandakombo, N, Mboukoulida, J, Semballa, S, Tagne, A, Tiendrébéogo, F, Erdmann, JB, van Antwerpen, T, Owor, BE, Flett, B, Ramusi, M, Windram, OP, Syed, R, Lett, JM, Briddon, RW, Markham, PG, Rybicki, EP & Varsani, A 2011, 'Reconstructing the history of maize streak virus strain a dispersal to reveal diversification hot spots and its origin in southern Africa', Journal of Virology, vol. 85, no. 18, pp. 9623-9636. https://doi.org/10.1128/JVI.00640-11
Monjane, Adérito L. ; Harkins, Gordon W. ; Martin, Darren P. ; Lemey, Philippe ; Lefeuvre, Pierre ; Shepherd, Dionne N. ; Oluwafemi, Sunday ; Simuyandi, Michelo ; Zinga, Innocent ; Komba, Ephrem K. ; Lakoutene, Didier P. ; Mandakombo, Noella ; Mboukoulida, Joseph ; Semballa, Silla ; Tagne, Appolinaire ; Tiendrébéogo, Fidèle ; Erdmann, Julia B. ; van Antwerpen, Tania ; Owor, Betty E. ; Flett, Bradley ; Ramusi, Moses ; Windram, Oliver P. ; Syed, Rizwan ; Lett, Jean Michel ; Briddon, Rob W. ; Markham, Peter G. ; Rybicki, Edward P. ; Varsani, Arvind. / Reconstructing the history of maize streak virus strain a dispersal to reveal diversification hot spots and its origin in southern Africa. In: Journal of Virology. 2011 ; Vol. 85, No. 18. pp. 9623-9636.
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AU - Lemey, Philippe

AU - Lefeuvre, Pierre

AU - Shepherd, Dionne N.

AU - Oluwafemi, Sunday

AU - Simuyandi, Michelo

AU - Zinga, Innocent

AU - Komba, Ephrem K.

AU - Lakoutene, Didier P.

AU - Mandakombo, Noella

AU - Mboukoulida, Joseph

AU - Semballa, Silla

AU - Tagne, Appolinaire

AU - Tiendrébéogo, Fidèle

AU - Erdmann, Julia B.

AU - van Antwerpen, Tania

AU - Owor, Betty E.

AU - Flett, Bradley

AU - Ramusi, Moses

AU - Windram, Oliver P.

AU - Syed, Rizwan

AU - Lett, Jean Michel

AU - Briddon, Rob W.

AU - Markham, Peter G.

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