Ethanedithiol in the presence of boron trifluoride etherate reacts with the spiroketal system of steroidal sapogenins to form the corresponding furostane 26-ethylenethioketal. Desulfurization leads to the furostane which in the 5α series was transformed into cholestan-16β-ol. Structural formulas are proposed to explain these reactions.
|Original language||English (US)|
|Number of pages||6|
|Journal||Journal of Organic Chemistry|
|State||Published - Jan 1 1959|
ASJC Scopus subject areas
- Organic Chemistry