Raman study of the low-frequency vibrations of polynucleotides

T. Weidlich, Stuart Lindsay

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


We have performed low-frequency Raman experiments on several polynucleotides with different sequences, conformations, and number of strands per helix. Below 200 cm-1 we have observed three Raman active intrahelical modes in A-DNA and B-DNA. Within one class of structure the modes show little sequence dependence. The bridging hydrogen bonds between the two strands only have a small influence on the frequency of the modes. The modes are strongly dependent on conformation and may therefore be useful as marker bands for structures and intrahelical interactions.

Original languageEnglish (US)
Pages (from-to)6479-6482
Number of pages4
JournalJournal of physical chemistry
Issue number23
StatePublished - Jan 1 1988

ASJC Scopus subject areas

  • Engineering(all)
  • Physical and Theoretical Chemistry


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