Protein microarrays as tools for functional proteomics

Joshua LaBaer, Niroshan Ramachandran

Research output: Contribution to journalReview article

218 Scopus citations

Abstract

Protein microarrays present an innovative and versatile approach to study protein abundance and function at an unprecedented scale. Given the chemical and structural complexity of the proteome, the development of protein microarrays has been challenging. Despite these challenges there has been a marked increase in the use of protein microarrays to map interactions of proteins with various other molecules, and to identify potential disease biomarkers, especially in the area of cancer biology. In this review, we discuss some of the promising advances made in the development and use of protein microarrays.

Original languageEnglish (US)
Pages (from-to)14-19
Number of pages6
JournalCurrent Opinion in Chemical Biology
Volume9
Issue number1
DOIs
StatePublished - Feb 2005
Externally publishedYes

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry

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