Abstract
The purified protein moiety of ribonuclease P. (EC 3.1.26.5) from Escherichia coli, a single polypeptide of molecular weight ~ 17 500, has no catalytic activity by itself on several RNA substrates. However, when it is mixed in vitro with an RNA species called M1 RNA, RNase P activity is reconstituted. The rate at which the purified RNase P cleaves any particular tRNA precursor molecule depends on the identity of that tRNA precursor.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1902-1906 |
| Number of pages | 5 |
| Journal | Biochemistry |
| Volume | 20 |
| Issue number | 7 |
| DOIs | |
| State | Published - Mar 1981 |
| Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry