Properties of a maonovalent and divalent requiring endoribonuclease with novel specificity from calf heart

Eiko Akaboshi, Sidney Altman

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

A new sonovalent and divalent requiring endoribonuclease hat been identified in extracts of calf heart titans using a natural substrate nolecule. This ribonuclease creates 5- hydroxyl and 3- phosphate groups in its cleavage products. It cleaves predominantly between pyrimidine and A residues though not all such possible sites are attacked in the substrates tested.

Original languageEnglish (US)
Pages (from-to)3687-3702
Number of pages16
JournalNucleic acids research
Volume11
Issue number11
DOIs
StatePublished - Jun 11 1983
Externally publishedYes

ASJC Scopus subject areas

  • Genetics

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