Preventing mental retardation associated with gross obesity in the Prader-Willi syndrome

K. A. Crnic, S. Sulzbacher, V. A. Holm, J. Snow

Research output: Contribution to journalArticle

27 Scopus citations

Abstract

27 patients with Prader-Willi syndrome have been described, ten of whom did not receive comprehensive management, nine who were diagnosed and treated after becoming obese, and eight who were diagnosed in infancy and responded to early preventative treatment. Intelligence scores declined in the first two groups, but the group receiving early treatment maintained a mean IQ score 20 points higher than the other two. Even though the underlying mechanism of this disorder remains undefined, a comprehensive early intervention program appears to improve prognosis.

Original languageEnglish (US)
Pages (from-to)787-789
Number of pages3
JournalPediatrics
Volume66
Issue number5
StatePublished - Dec 1 1980

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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    Crnic, K. A., Sulzbacher, S., Holm, V. A., & Snow, J. (1980). Preventing mental retardation associated with gross obesity in the Prader-Willi syndrome. Pediatrics, 66(5), 787-789.