Population Structure of Macaca fascicularis aurea, and their Genetic Relationships with M. f. fascicularis and M. mulatta Determined by 868 RADseq-Derived Autosomal SNPs—A consideration for biomedical research

Poompat Phadphon, Sree Kanthaswamy, Robert F. Oldt, Yuzuru Hamada, Suchinda Malaivijitnond

Research output: Contribution to journalArticlepeer-review

Abstract

Background: This study examined the population structure of Macaca fascicularis aurea and their genetic relationships with M. f. fascicularis and M. mulatta. Methods: The study analyzed 868 RADseq-derived SNPs from samples representing the entire distribution range of M. f. aurea, including their inter- and intraspecific hybrid zones. Results: The study supports a M. mulatta/Indochinese M. f. fascicularis, Sundaic M. f. fascicularis, and M. f. aurea trichotomy; M. f. aurea was genetically distinct from both forms of M. f. fascicularis and M. mulatta. Hybridization between M. f. aurea and M. f. fascicularis occurred in two directions: south-north (8°25′ to 15°56′) and west-east (98°28′ to 99°02′). Low levels of M. mulatta introgression were also detected in M. f. aurea. Conclusion: This study showcases a complicated scenario of genetic relationships between the M. fascicularis subspecies and between M. fascicularis and M. mulatta and underscores the importance of these taxa's population structure and genetic relationships for biomedical research.

Original languageEnglish (US)
Pages (from-to)33-44
Number of pages12
JournalJournal of Medical Primatology
Volume51
Issue number1
DOIs
StateAccepted/In press - 2021
Externally publishedYes

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

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