Polymicrobial oral infection with four periodontal bacteria orchestrates a distinct inflammatory response and atherosclerosis in ApoE^null mice

Agriculture & Biology

• atherosclerosis 100%
• inflammation 81%
• mouth 69%
• interleukin-13 58%
• mice 51%
• bacteria 49%
• infection 47%
• chemokine CCL5 43%
• microbiome 37%
• periodontal diseases 35%
• risk factors 24%
• CXCR4 receptor 23%
• chemokine CXCL12 23%
• Forsythia 20%
• Treponema denticola 19%
• Fusobacterium nucleatum 18%
• vascular diseases 18%
• Porphyromonas gingivalis 17%
• chylomicrons 17%
• chemokines 16%
• interleukin-4 15%
• interleukin-1 15%
• aorta 13%
• cytokines 12%
• T-lymphocytes 11%
• ligands 11%
• nitric oxide 11%
• animal models 11%
• immune response 10%
• lesions (animal) 10%
• triacylglycerols 10%
• heart 9%
• cholesterol 9%
• screening 9%
• gene expression 7%
• pathogens 7%
• lipids 6%
• DNA 6%
• tissues 5%
• genes 4%

Medicine & Life Sciences

• Coinfection 86%
• Atherosclerosis 72%
• Bacteria 60%
• Interleukin-13 43%
• Infections 42%
• Atherosclerotic Plaques 40%
• Microbiota 37%
• Chemokine CCL5 32%
• Periodontal Diseases 27%
• Forsythia 22%
• lymphotactin 21%
• Treponema denticola 19%
• Fusobacterium nucleatum 18%
• Chylomicrons 17%
• very low density lipoprotein triglyceride 17%
• Porphyromonas gingivalis 15%
• Fas Ligand Protein 15%
• Apolipoproteins B 14%
• Granulocyte-Macrophage Colony-Stimulating Factor 13%
• oxidized low density lipoprotein 12%
• Interleukin-1 12%
• Vascular Diseases 12%
• Chemokines 11%
• Interleukin-4 11%
• Serum 11%
• Aorta 11%
• Mouth 10%
• Nitric Oxide 10%
• Cholesterol 9%
• Lipids 8%
• Heart 8%
• Cytokines 7%
• T-Lymphocytes 7%
• Gene Expression 7%
• DNA 7%
• Genes 5%

Chemical Compounds

• Oxidised LDL 49%
• Hyperlipidemic 47%
• Triglyceride 31%
• Molecule 30%
• Nitric Oxide 28%
• Cholesterol 26%
• Lipid 20%
• Ligand 13%