Polymer Stereocomplexation as a Scalable Platform for Nanoparticle Assembly

Allison Abdilla, Neil D. Dolinski, Puck De Roos, Jing Ming Ren, Erika Van Der Woude, Soyoung E. Seo, Manuel S. Zayas, Jimmy Lawrence, Javier Read De Alaniz, Craig J. Hawker

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

DNA-mediated assembly of inorganic particles has demonstrated to be a powerful approach for preparing nanomaterials with a range of interesting optical and electrical properties. Building on this inspiration, we describe a generalizable gram-scale method to assemble nanoparticles through the formation of poly(methyl methacrylate) (PMMA) triple-helices. In this work, alkene-terminated syndiotactic (st-) and isotactic (it-) PMMA polymers were prepared and subsequently functionalized to afford nanoparticle ligands. Nanoparticles with complementary st- and it-PMMA ligands could then be spontaneously assembled upon mixing at room temperature. This process was robust and fully reversible through multiple heating and cooling cycles. The versatility of PMMA stereocomplexation was highlighted by assembling hybrid structures composed of nanoparticles of different compositions (e.g., Au and quantum dots) and shapes (e.g., spheres and rods). These initial demonstrations of nanoparticle self-assembly from inexpensive PMMA-based materials present an attractive alternative to DNA-based nanomaterials.

Original languageEnglish (US)
Pages (from-to)1667-1672
Number of pages6
JournalJournal of the American Chemical Society
Volume142
Issue number4
DOIs
StatePublished - Jan 29 2020
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

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