Piet Mondrian's trees and the evolution in understanding multiple sclerosis, Charcot Prize Lecture 2011

Lawrence Steinman, Robert C. Axtell, Donald Barbieri, Roopa Bhat, Sara Brownell, Brigit A. De Jong, Shannon E. Dunn, Jacqueline L. Grant, May H. Han, Peggy P. Ho, Hedwich F. Kuipers, Michael P. Kurnellas, Shalina S. Ousman, Jonathan B. Rothbard

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Four questions were posed about multiple sclerosis (MS) at the 2011 Charcot Lecture, Oct. 22, 2011. 1. The Male/Female Disparity: Why are women developing MS so much more frequently than men? 2. Neuronal and Glial Protection: Are there guardian molecules that protect the nervous system in MS? 3. Predictive Medicine: With all the approved drugs, how can we rationally decide which one to use? 4. The Precise Scalpel vs. the Big Hammer for Therapy: Is antigen-specific therapy for demyelinating disease possible? To emphasize how our views on the pathogenesis and treatment of MS are evolving, and given the location of the talk in Amsterdam, Piet Mondrian's progressive interpretations of trees serve as a heuristic.

Original languageEnglish (US)
Pages (from-to)5-14
Number of pages10
JournalMultiple Sclerosis
Volume19
Issue number1
DOIs
StatePublished - 2013
Externally publishedYes

Fingerprint

Multiple Sclerosis
Demyelinating Diseases
Neuroglia
Nervous System
Therapeutics
Medicine
Antigens
Pharmaceutical Preparations

Keywords

  • Charcot Lecture
  • Multiple sclerosis

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Cite this

Piet Mondrian's trees and the evolution in understanding multiple sclerosis, Charcot Prize Lecture 2011. / Steinman, Lawrence; Axtell, Robert C.; Barbieri, Donald; Bhat, Roopa; Brownell, Sara; De Jong, Brigit A.; Dunn, Shannon E.; Grant, Jacqueline L.; Han, May H.; Ho, Peggy P.; Kuipers, Hedwich F.; Kurnellas, Michael P.; Ousman, Shalina S.; Rothbard, Jonathan B.

In: Multiple Sclerosis, Vol. 19, No. 1, 2013, p. 5-14.

Research output: Contribution to journalArticle

Steinman, L, Axtell, RC, Barbieri, D, Bhat, R, Brownell, S, De Jong, BA, Dunn, SE, Grant, JL, Han, MH, Ho, PP, Kuipers, HF, Kurnellas, MP, Ousman, SS & Rothbard, JB 2013, 'Piet Mondrian's trees and the evolution in understanding multiple sclerosis, Charcot Prize Lecture 2011', Multiple Sclerosis, vol. 19, no. 1, pp. 5-14. https://doi.org/10.1177/1352458512470730
Steinman, Lawrence ; Axtell, Robert C. ; Barbieri, Donald ; Bhat, Roopa ; Brownell, Sara ; De Jong, Brigit A. ; Dunn, Shannon E. ; Grant, Jacqueline L. ; Han, May H. ; Ho, Peggy P. ; Kuipers, Hedwich F. ; Kurnellas, Michael P. ; Ousman, Shalina S. ; Rothbard, Jonathan B. / Piet Mondrian's trees and the evolution in understanding multiple sclerosis, Charcot Prize Lecture 2011. In: Multiple Sclerosis. 2013 ; Vol. 19, No. 1. pp. 5-14.
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