PI3K inhibitors protect against glucocorticoid-induced skin atrophy

Medicine & Life Sciences

• Phosphoinositide-3 Kinase Inhibitors 82%
• Glucocorticoids 52%
• DNA Damage 50%
• Atrophy 50%
• Fluocinolone Acetonide 40%
• Glucocorticoid Receptors 36%
• Phosphatidylinositol 3-Kinase 33%
• Skin 31%
• 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 19%
• Keratinocytes 16%
• tacrolimus binding protein 5 15%
• (5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol 15%
• Drug Repositioning 11%
• Wortmannin 10%
• Organized Financing 9%
• Chromatin Immunoprecipitation 9%
• Reporter Genes 8%
• Skin Diseases 7%
• Computational Biology 7%
• Libraries 7%
• Ear 7%
• Edema 6%
• Steroids 6%
• Anti-Inflammatory Agents 6%
• Phosphorylation 5%
• Pharmacology 5%
• Gene Expression 4%
• Genes 3%
• Therapeutics 1%

Chemical Compounds

• Phosphatidylinositol 3 Kinase Inhibitor 100%
• Glucocorticoid 74%
• Protein Kinase B Inhibitor 31%
• LY294002 21%
• Fluocinolone Acetonide 21%
• Fluocinolone 12%
• Proliferative 7%
• Catabolic 7%
• Microarrays 6%
• Antiinflammatory 5%
• Steroid 5%
• Block Like Crystal 3%
• Drug 3%
• Protein 2%
• Application 1%