Phylogenetic incongruence in the Drosophila melanogaster species group

Alex Wong, Jeffrey Jensen, John E. Pool, Charles F. Aquadro

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Drosophila melanogaster and its close relatives are used extensively in comparative biology. Despite the importance of phylogenetic information for such studies, relationships between some melanogaster species group members are unclear due to conflicting phylogenetic signals at different loci. In this study, we use twelve nuclear loci (eleven coding and one non-coding) to assess the degree of phylogenetic incongruence in this model system. We focus on two nodes: (1) the node joining the Drosophila erecta-Drosophila orena, Drosophila melanogaster-Drosophila simulans, and Drosophila yakuba-Drosophila teissieri lineages, and (2) the node joining the lineages leading to the melanogaster, takahashii, and eugracilis subgroups. We find limited evidence for incongruence at the first node; our data, as well as those of several previous studies, strongly support monophyly of a clade consisting of D. erecta-D. orena and D. yakuba-D. teissieri. By contrast, using likelihood based tests of congruence, we find robust evidence for topological incongruence at the second node. Different loci support different relationships among the melanogaster, takahashii, and eugracilis subgroups, and the observed incongruence is not easily attributable to homoplasy, non-equilibrium base composition, or positive selection on a subset of loci. We argue that lineage sorting in the common ancestor of these three subgroups is the most plausible explanation for our observations. Such lineage sorting may lead to biased estimation of tree topology and evolutionary rates, and may confound inferences of positive selection.

Original languageEnglish (US)
Pages (from-to)1138-1150
Number of pages13
JournalMolecular Phylogenetics and Evolution
Volume43
Issue number3
DOIs
StatePublished - Jun 2007
Externally publishedYes

Fingerprint

Drosophila melanogaster
Melanogaster
Drosophila
Drosophila yakuba
phylogenetics
sorting
loci
phylogeny
common ancestry
Drosophila simulans
topology
Base Composition
monophyly
ancestry
Biological Sciences
testing

Keywords

  • Drosophila
  • Incongruence
  • Lineage sorting
  • Melanogaster subgroup
  • Phylogeny
  • Recombination

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Molecular Biology
  • Genetics

Cite this

Phylogenetic incongruence in the Drosophila melanogaster species group. / Wong, Alex; Jensen, Jeffrey; Pool, John E.; Aquadro, Charles F.

In: Molecular Phylogenetics and Evolution, Vol. 43, No. 3, 06.2007, p. 1138-1150.

Research output: Contribution to journalArticle

Wong, Alex ; Jensen, Jeffrey ; Pool, John E. ; Aquadro, Charles F. / Phylogenetic incongruence in the Drosophila melanogaster species group. In: Molecular Phylogenetics and Evolution. 2007 ; Vol. 43, No. 3. pp. 1138-1150.
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