Optimal step-type designs for comparing test treatments with a control

Ching Shui Cheng, Dibyen Majumdar, John Stufken, Tahsin Erkan Türe

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

The problem of obtaining A-optimal designs for comparing v test treatments with a control in b blocks of size k each is considered. A condition on the parameters (u, b, k) is identified for which optimal step-type designs can be obtained. Families of such designs are given. Methods of searching for highly efficient designs are proposed for situations in which it is difficult to determine an A-optimal design. Under the usual additive homoscedastic model, an A-optimal design minimizes the average variance of the least squares estimators of the control-test treatment comparisons. Majumdar and Notz (1983) gave a method for finding A-optimal designs. Their optimal designs can basically be of two types, using the terminology of Hedayat and Majumdar (1984): rectangular (R), in which every block has the same number of replications of the control, and step (5), in which some blocks contain the control t times and the others t + 1 times. Optimal R-type designs were studied by Hedayat and Majumdar (1985). Families of such designs, particularly when each block has one replication of the control, were given in that paper. In this article, we intend to study optimal S-type designs. Step-type designs are more complicated than rectangular-type designs; the latter are balanced incomplete block designs in the test treatments augmented by an equal number of controls in each block, but the former do not have such a simple characterization. Consequently, both the optimality and the construction of such designs are more involved.

Original languageEnglish (US)
Pages (from-to)477-482
Number of pages6
JournalJournal of the American Statistical Association
Volume83
Issue number402
DOIs
StatePublished - Jun 1988

Keywords

  • A-optimal design
  • Balanced incomplete block design
  • Balanced treatment incomplete block design

ASJC Scopus subject areas

  • Statistics and Probability
  • Statistics, Probability and Uncertainty

Fingerprint Dive into the research topics of 'Optimal step-type designs for comparing test treatments with a control'. Together they form a unique fingerprint.

Cite this