On the unfounded enthusiasm for soft selective sweeps

Research output: Contribution to journalReview article

59 Scopus citations

Abstract

Underlying any understanding of the mode, tempo and relative importance of the adaptive process in the evolution of natural populations is the notion of whether adaptation is mutation limited. Two very different population genetic models have recently been proposed in which the rate of adaptation is not strongly limited by the rate at which newly arising beneficial mutations enter the population. However, empirical and experimental evidence to date challenges the recent enthusiasm for invoking these models to explain observed patterns of variation in humans and Drosophila.

Original languageEnglish (US)
Article number5281
JournalNature communications
Volume5
DOIs
StatePublished - 2014
Externally publishedYes

ASJC Scopus subject areas

  • Chemistry(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Physics and Astronomy(all)

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