Multipoint gene mapping using seriation. I. General methods

Kenneth Buetow, A. Chakravarti

Research output: Contribution to journalArticle

57 Scopus citations

Abstract

Initial and accurate inference of locus order and estimates of interlocus distances and interference can be obtained using seriation techniques. The analysis requires a matrix of recombination values that can be estimated by standard pairwise linkage analysis. This allows combination of results from individual investigators without reanalysis of basic pedigree material. Seriation can be performed without the use of a computer.

Original languageEnglish (US)
Pages (from-to)180-188
Number of pages9
JournalAmerican Journal of Human Genetics
Volume41
Issue number2
Publication statusPublished - 1987
Externally publishedYes

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ASJC Scopus subject areas

  • Genetics

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