Modeling biofilm biodegradation requiring cosubstrates: The quinoline example

M. J. Malmstead, F. J. Brockman, A. J. Valocchi, Bruce Rittmann

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

The aerobic biodegradation of quinoline, a two-ring nitrogen heterocycle, offers an outstanding example of when structured modeling including cosubstrates is required for a biofilm system. In this case, the cosubstrate is oxygen, which is used as a direct cosubstrate in oxygenase reactions and as a primary electron acceptor in respiration. Quinoline biodegradation is numerically simulated as occurring in five key steps, two of which involve oxygen as a direct cosubstrate. Modeling evaluation of experimental results from a laboratory-scale biofilm column shows that the oxygenation steps are much more sensitive to low oxygen concentrations than are steps in which oxygen only participates through respiration. The result of this differential oxygen sensitivity is that the first intermediate product, 2-hydroxyquinoline, builds up, because its degradation through an oxygenase reaction is slowed preferentially by oxygen depletion.

Original languageEnglish (US)
Pages (from-to)71-84
Number of pages14
JournalWater Science and Technology
Volume31
Issue number1
DOIs
StatePublished - 1995
Externally publishedYes

Fingerprint

Biofilms
Biodegradation
biofilm
biodegradation
oxygen
Oxygen
modeling
respiration
Oxygenation
oxygenation
Nitrogen
Degradation
electron
degradation
Electrons
nitrogen

Keywords

  • Biofilm
  • Cosubstrates
  • Oxygen limitation
  • Oxygenation
  • Quinoline
  • Structured modeling

ASJC Scopus subject areas

  • Water Science and Technology

Cite this

Modeling biofilm biodegradation requiring cosubstrates : The quinoline example. / Malmstead, M. J.; Brockman, F. J.; Valocchi, A. J.; Rittmann, Bruce.

In: Water Science and Technology, Vol. 31, No. 1, 1995, p. 71-84.

Research output: Contribution to journalArticle

Malmstead, M. J. ; Brockman, F. J. ; Valocchi, A. J. ; Rittmann, Bruce. / Modeling biofilm biodegradation requiring cosubstrates : The quinoline example. In: Water Science and Technology. 1995 ; Vol. 31, No. 1. pp. 71-84.
@article{82709e3817a24b2293700168dadae5db,
title = "Modeling biofilm biodegradation requiring cosubstrates: The quinoline example",
abstract = "The aerobic biodegradation of quinoline, a two-ring nitrogen heterocycle, offers an outstanding example of when structured modeling including cosubstrates is required for a biofilm system. In this case, the cosubstrate is oxygen, which is used as a direct cosubstrate in oxygenase reactions and as a primary electron acceptor in respiration. Quinoline biodegradation is numerically simulated as occurring in five key steps, two of which involve oxygen as a direct cosubstrate. Modeling evaluation of experimental results from a laboratory-scale biofilm column shows that the oxygenation steps are much more sensitive to low oxygen concentrations than are steps in which oxygen only participates through respiration. The result of this differential oxygen sensitivity is that the first intermediate product, 2-hydroxyquinoline, builds up, because its degradation through an oxygenase reaction is slowed preferentially by oxygen depletion.",
keywords = "Biofilm, Cosubstrates, Oxygen limitation, Oxygenation, Quinoline, Structured modeling",
author = "Malmstead, {M. J.} and Brockman, {F. J.} and Valocchi, {A. J.} and Bruce Rittmann",
year = "1995",
doi = "10.1016/0273-1223(95)00156-H",
language = "English (US)",
volume = "31",
pages = "71--84",
journal = "Water Science and Technology",
issn = "0273-1223",
publisher = "IWA Publishing",
number = "1",

}

TY - JOUR

T1 - Modeling biofilm biodegradation requiring cosubstrates

T2 - The quinoline example

AU - Malmstead, M. J.

AU - Brockman, F. J.

AU - Valocchi, A. J.

AU - Rittmann, Bruce

PY - 1995

Y1 - 1995

N2 - The aerobic biodegradation of quinoline, a two-ring nitrogen heterocycle, offers an outstanding example of when structured modeling including cosubstrates is required for a biofilm system. In this case, the cosubstrate is oxygen, which is used as a direct cosubstrate in oxygenase reactions and as a primary electron acceptor in respiration. Quinoline biodegradation is numerically simulated as occurring in five key steps, two of which involve oxygen as a direct cosubstrate. Modeling evaluation of experimental results from a laboratory-scale biofilm column shows that the oxygenation steps are much more sensitive to low oxygen concentrations than are steps in which oxygen only participates through respiration. The result of this differential oxygen sensitivity is that the first intermediate product, 2-hydroxyquinoline, builds up, because its degradation through an oxygenase reaction is slowed preferentially by oxygen depletion.

AB - The aerobic biodegradation of quinoline, a two-ring nitrogen heterocycle, offers an outstanding example of when structured modeling including cosubstrates is required for a biofilm system. In this case, the cosubstrate is oxygen, which is used as a direct cosubstrate in oxygenase reactions and as a primary electron acceptor in respiration. Quinoline biodegradation is numerically simulated as occurring in five key steps, two of which involve oxygen as a direct cosubstrate. Modeling evaluation of experimental results from a laboratory-scale biofilm column shows that the oxygenation steps are much more sensitive to low oxygen concentrations than are steps in which oxygen only participates through respiration. The result of this differential oxygen sensitivity is that the first intermediate product, 2-hydroxyquinoline, builds up, because its degradation through an oxygenase reaction is slowed preferentially by oxygen depletion.

KW - Biofilm

KW - Cosubstrates

KW - Oxygen limitation

KW - Oxygenation

KW - Quinoline

KW - Structured modeling

UR - http://www.scopus.com/inward/record.url?scp=0029030718&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029030718&partnerID=8YFLogxK

U2 - 10.1016/0273-1223(95)00156-H

DO - 10.1016/0273-1223(95)00156-H

M3 - Article

AN - SCOPUS:0029030718

VL - 31

SP - 71

EP - 84

JO - Water Science and Technology

JF - Water Science and Technology

SN - 0273-1223

IS - 1

ER -