Measuring the number concentration of arbitrarily-shaped gold nanoparticles with surface plasmon resonance microscopy

Xiang Wo, Yashuang Luo, Nongjian Tao, Wei Wang, Hong Yuan Chen

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Molar concentration of gold nanoparticles is one of the most critical parameters of gold colloids in order to develop their applications in sensing, diagnostics and nanomedicine. Previous methods often stand just for gold nanoparticles with regular shape and narrow size distribution. In the present work, we proposed an absolute quantification method that determined the molar concentration of gold nanoparticles with arbitrary shapes and polydisperse sizes. This approach involved the real time monitoring and counting of individual nanoparticles collision events, from which the quantification of molar concentration was achieved using a theoretical model consisting of Fick’s laws of diffusion and Stokes-Einstein equation. The determination of spherical gold nanoparticles concentration resulted in excellent agreement with traditional spectrometry method. It was further demonstrated that the present approach can be expanded to determine the molar concentration of gold nanoparticles with arbitrary shapes and poly-diversed distributions.

Original languageEnglish (US)
Pages (from-to)843-847
Number of pages5
JournalScience China Chemistry
Volume59
Issue number7
DOIs
StatePublished - Jul 1 2016
Externally publishedYes

Fingerprint

Surface plasmon resonance
Gold
Microscopic examination
Nanoparticles
Medical nanotechnology
Gold Colloid
Spectrometry
Monitoring

Keywords

  • gold nanoparticles
  • number concentration
  • surface plasmon resonance microscopy

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Measuring the number concentration of arbitrarily-shaped gold nanoparticles with surface plasmon resonance microscopy. / Wo, Xiang; Luo, Yashuang; Tao, Nongjian; Wang, Wei; Chen, Hong Yuan.

In: Science China Chemistry, Vol. 59, No. 7, 01.07.2016, p. 843-847.

Research output: Contribution to journalArticle

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