Mass spectra of ribonucleoside components of tRNA. II

Sidney M. Hecht, Amrit S. Gupta, Nelson J. Leonard

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

We have obtained low-resolution mass spectra under as uniform conditions as possible at 20 and 70 eV for the following ribonucleosides: cytidine, uridine, adenosine, 5-hydroxymethyluridine, 2-methyladenosine, 2′-O-methyladenosine, isoguanosine, xanthosine, 2′-O-methylguanosine, N2,N2-dimethylguanosine, N6-(3-methyl-2-butenyl)adenosine, N6-(3-methyl-3-butenyl)adenosine, ribosylzeatin, N6-(3-hydroxy-3-methyl-butyl)adenosine, ribosyldihydrozeatin, and N6-(3-methyl-2-butenyl)-2-methylthioadenosine. All these ribonucleosides are components, or possible components, of tRNA. The spectra are intended as reference spectra for the structural confirmation of known nucleosides from tRNA and for the identification of unknown, modified nucleosides by comparison of their fragmentation pattern with those already recorded.

Original languageEnglish (US)
Pages (from-to)230-251
Number of pages22
JournalAnalytical Biochemistry
Volume38
Issue number1
DOIs
StatePublished - Nov 1970
Externally publishedYes

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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