Isolation and structure of pancratistatin

George Pettit, Venkatswamy Gaddamidi, Gordon M. Cragg, Delbert L. Herald, Yoneo Sagawa

Research output: Contribution to journalArticlepeer-review

133 Scopus citations

Abstract

Pancratium littorale Jacq. collected in Hawaii has been found to produce a new phenanthridone, pancratistatin, that significantly inhibits growth of the murine P388 lymphocytic leukaemia; an X-ray crystal structure determination of pancratistatin monomethyl ether (1c) was employed to assign structure (1a) to pancratistatin.

Original languageEnglish (US)
Pages (from-to)1693-1694
Number of pages2
JournalJournal of the Chemical Society, Chemical Communications
Issue number24
DOIs
StatePublished - Jan 1 1984

ASJC Scopus subject areas

  • Molecular Medicine

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