Abstract

Hydrogels are promising for a variety of medical applications due to their high water content and mechanical similarity to natural tissues. When made injectable, hydrogels can reduce the invasiveness of application, which in turn reduces surgical and recovery costs. Key schemes used to make hydrogels injectable include in situ formation due to physical and/or chemical cross-linking. Advances in polymer science have provided new injectable hydrogels for applications in drug delivery and tissue engineering. A number of these injectable hydrogel systems have reached the clinic and impact the health care of many patients. However, a significant remaining challenge is translating the ever-growing family of injectable hydrogels developed in laboratories around the world to the clinic.

Original languageEnglish (US)
Pages (from-to)881-903
Number of pages23
JournalJournal of Polymer Science, Part B: Polymer Physics
Volume50
Issue number13
DOIs
StatePublished - Jul 1 2012

Keywords

  • drug delivery
  • in situ forming
  • injectable hydrogels
  • temperature-responsive
  • tissue engineering

ASJC Scopus subject areas

  • Condensed Matter Physics
  • Physical and Theoretical Chemistry
  • Polymers and Plastics
  • Materials Chemistry

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