Influence of polycation molecular weight on poly(2-dimethylaminoethyl methacrylate)-mediated DNA delivery in vitro

Medicine & Life Sciences

• poly(2-(dimethylamino)ethyl methacrylate) 100%
• polycations 76%
• Molecular Weight 43%
• DNA 29%
• In Vitro Techniques 22%
• Transfection 17%
• Plasmids 12%
• Competitive Binding 6%
• Deoxyribonucleases 6%
• Polymerization 5%
• Reporter Genes 5%
• Free Radicals 4%
• Luciferases 4%
• Genetic Therapy 4%
• Heparin 4%
• Polymers 4%
• Gels 4%
• Poisons 3%
• Endothelial Cells 3%
• Weights and Measures 3%
• Gene Expression 3%
• Membranes 3%
• Brain 2%

Engineering & Materials Science

• Molecular weight 58%
• DNA 53%
• Assays 12%
• Deoxyribonucleases 9%
• Gene therapy 9%
• Heparin 8%
• Free radical polymerization 8%
• Cytotoxicity 7%
• Endothelial cells 7%
• Toxicity 6%
• Gene expression 5%
• Gels 5%
• Membranes 4%
• Brain 4%
• Polymers 3%
• Experiments 1%

Chemical Compounds

• Polycationic Polymer 60%
• Methacrylate 43%
• Weight 27%
• Mass Average Molar Mass 6%
• Heparin 6%
• Radical Polimerization 5%
• Kd 4%
• Toxic 4%
• Resistance 3%
• Gel 3%