Immunological and functional characterization of Mycobacterium leprae protein antigens: An overview

Jelle E.R. Thole, Brigitte Wieles, Josephine E. Clark-Curtiss, Tom H.M. Ottenhoff, Tobias F. Rinke De Wit

Research output: Contribution to journalReview articlepeer-review

31 Scopus citations

Abstract

A major focus of leprosy research in the last 10 years has been the identification and characterization of antigens of Mycobacterium leprae that interact with antibodies and T cells of the host's immune response. Through the combined efforts of many different laboratories, a substantial number of protein antigens have been identified and characterized. In this MicroReview we present an updated list of M. leprae protein antigens, and, with emphasis on recent developments, summarize what is known regarding their functional and immunological features.

Original languageEnglish (US)
Pages (from-to)791-800
Number of pages10
JournalMolecular Microbiology
Volume18
Issue number5
DOIs
StatePublished - Dec 1995

ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology

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