General Similarities but Consistent Differences between Early-and Late-Onset Depression among Korean Adults Aged 40 and Older

Jee Eun Park, Ji Hoon Sohn, Su Jeong Seong, Hye Won Suk, Maeng Je Cho

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Differences in clinical characteristics, symptomatology, and psychiatric comorbidity between early-onset depression (EOD) and late-onset depression (LOD) were examined in a nationwide representative sample. The Korean Composite International Diagnostic Interview was used to investigate psychiatric diagnoses and age of onset. A total of 319 subjects aged 40 years and older with a current major depressive disorder (MDD) were included, and both a continuous and a dichotomous (40 years) age-of-onset indicator were used in the analyses. Despite general similarities between groups, EOD was related to chronic (recurrent and longer episode) and severe (higher lifetime suicidality) clinical features. Hypersomnia and suicidal plans/attempts were associated with EOD, whereas anhedonia was related to LOD. Lifetime generalized anxiety disorder was associated with EOD, whereas dysthymic disorder was related with higher age of MDD onset. This study provides additional evidence of consistent differences between EOD and LOD among middle-aged and older Asians.

Original languageEnglish (US)
Pages (from-to)617-625
Number of pages9
JournalJournal of Nervous and Mental Disease
Volume203
Issue number8
DOIs
StatePublished - Aug 14 2015

Keywords

  • age of onset
  • comorbidity
  • Depressive disorder
  • Korean adults
  • phenomenology

ASJC Scopus subject areas

  • Psychiatry and Mental health

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