Abstract

Acidogenic diets, commonly measured by the potential renal acid load (PRAL), have been linked with metabolic diseases including insulin resistance, hepatic dysfunction, and cardiometabolic risk. Vegan diets are linked to low dietary acid loads, but the degree of adherence to a vegan diet to demonstrate this benefit is unknown. This study compared the change in PRAL and urine pH of omnivores who followed a vegan diet for either 2, 3, or 7 days over one week. Healthy adults were recruited from a campus population and randomly assigned to one of the three groups: VEG7 (vegan diet followed for seven consecutive days); VEG3 (vegan diet followed for three evenly spaced days over one week); or VEG2 (vegan diet followed for two evenly spaced days over one week). Gender, age, and body mass index did not differ between groups (overall: 21.8 ± 2.4 y and 24.4 ± 5.6 kg/m2). Following the one week intervention, outcome measures did not vary between the VEG2 and VEG3 groups, and these groups were collapsed for the final analyses. The 24-h urine pH was raised after seven consistent days of vegan diet adherence and was unchanged after 2–3 days of vegan diet adherence over the course of a week (+0.52 ± 0.69 and −0.02 ± 0.56 respectively, p = 0.048). However, dietary PRAL scores fell significantly in both dietary groups during the 7-day trial. Since low dietary PRAL scores have been related to improve metabolic parameters, adoption of a vegan diets for several days per week should be explored as a diet strategy to lower disease risk.

Original languageEnglish (US)
Pages (from-to)1-6
Number of pages6
JournalPlant Foods for Human Nutrition
DOIs
StateAccepted/In press - Jul 4 2017

Fingerprint

acid-base balance
Acid-Base Equilibrium
Nutrition
Acids
kidneys
acids
Kidney
urine
Urine
Diet
vegan diet
Vegan Diet
Metabolic Diseases
omnivores
metabolic diseases
insulin resistance
diet
body mass index
Insulin Resistance
Body Mass Index

Keywords

  • Potential renal acid load
  • Urine pH
  • Vegan diets

ASJC Scopus subject areas

  • Chemistry (miscellaneous)
  • Food Science

Cite this

Examining the Impact of Adherence to a Vegan Diet on Acid-Base Balance in Healthy Adults. / Cosgrove, Kelly; Johnston, Carol.

In: Plant Foods for Human Nutrition, 04.07.2017, p. 1-6.

Research output: Contribution to journalArticle

@article{2845b2ffc7ba4802b74ac6938beefb78,
title = "Examining the Impact of Adherence to a Vegan Diet on Acid-Base Balance in Healthy Adults",
abstract = "Acidogenic diets, commonly measured by the potential renal acid load (PRAL), have been linked with metabolic diseases including insulin resistance, hepatic dysfunction, and cardiometabolic risk. Vegan diets are linked to low dietary acid loads, but the degree of adherence to a vegan diet to demonstrate this benefit is unknown. This study compared the change in PRAL and urine pH of omnivores who followed a vegan diet for either 2, 3, or 7 days over one week. Healthy adults were recruited from a campus population and randomly assigned to one of the three groups: VEG7 (vegan diet followed for seven consecutive days); VEG3 (vegan diet followed for three evenly spaced days over one week); or VEG2 (vegan diet followed for two evenly spaced days over one week). Gender, age, and body mass index did not differ between groups (overall: 21.8 ± 2.4 y and 24.4 ± 5.6 kg/m2). Following the one week intervention, outcome measures did not vary between the VEG2 and VEG3 groups, and these groups were collapsed for the final analyses. The 24-h urine pH was raised after seven consistent days of vegan diet adherence and was unchanged after 2–3 days of vegan diet adherence over the course of a week (+0.52 ± 0.69 and −0.02 ± 0.56 respectively, p = 0.048). However, dietary PRAL scores fell significantly in both dietary groups during the 7-day trial. Since low dietary PRAL scores have been related to improve metabolic parameters, adoption of a vegan diets for several days per week should be explored as a diet strategy to lower disease risk.",
keywords = "Potential renal acid load, Urine pH, Vegan diets",
author = "Kelly Cosgrove and Carol Johnston",
year = "2017",
month = "7",
day = "4",
doi = "10.1007/s11130-017-0620-7",
language = "English (US)",
pages = "1--6",
journal = "Plant Foods for Human Nutrition",
issn = "0921-9668",
publisher = "Springer Netherlands",

}

TY - JOUR

T1 - Examining the Impact of Adherence to a Vegan Diet on Acid-Base Balance in Healthy Adults

AU - Cosgrove, Kelly

AU - Johnston, Carol

PY - 2017/7/4

Y1 - 2017/7/4

N2 - Acidogenic diets, commonly measured by the potential renal acid load (PRAL), have been linked with metabolic diseases including insulin resistance, hepatic dysfunction, and cardiometabolic risk. Vegan diets are linked to low dietary acid loads, but the degree of adherence to a vegan diet to demonstrate this benefit is unknown. This study compared the change in PRAL and urine pH of omnivores who followed a vegan diet for either 2, 3, or 7 days over one week. Healthy adults were recruited from a campus population and randomly assigned to one of the three groups: VEG7 (vegan diet followed for seven consecutive days); VEG3 (vegan diet followed for three evenly spaced days over one week); or VEG2 (vegan diet followed for two evenly spaced days over one week). Gender, age, and body mass index did not differ between groups (overall: 21.8 ± 2.4 y and 24.4 ± 5.6 kg/m2). Following the one week intervention, outcome measures did not vary between the VEG2 and VEG3 groups, and these groups were collapsed for the final analyses. The 24-h urine pH was raised after seven consistent days of vegan diet adherence and was unchanged after 2–3 days of vegan diet adherence over the course of a week (+0.52 ± 0.69 and −0.02 ± 0.56 respectively, p = 0.048). However, dietary PRAL scores fell significantly in both dietary groups during the 7-day trial. Since low dietary PRAL scores have been related to improve metabolic parameters, adoption of a vegan diets for several days per week should be explored as a diet strategy to lower disease risk.

AB - Acidogenic diets, commonly measured by the potential renal acid load (PRAL), have been linked with metabolic diseases including insulin resistance, hepatic dysfunction, and cardiometabolic risk. Vegan diets are linked to low dietary acid loads, but the degree of adherence to a vegan diet to demonstrate this benefit is unknown. This study compared the change in PRAL and urine pH of omnivores who followed a vegan diet for either 2, 3, or 7 days over one week. Healthy adults were recruited from a campus population and randomly assigned to one of the three groups: VEG7 (vegan diet followed for seven consecutive days); VEG3 (vegan diet followed for three evenly spaced days over one week); or VEG2 (vegan diet followed for two evenly spaced days over one week). Gender, age, and body mass index did not differ between groups (overall: 21.8 ± 2.4 y and 24.4 ± 5.6 kg/m2). Following the one week intervention, outcome measures did not vary between the VEG2 and VEG3 groups, and these groups were collapsed for the final analyses. The 24-h urine pH was raised after seven consistent days of vegan diet adherence and was unchanged after 2–3 days of vegan diet adherence over the course of a week (+0.52 ± 0.69 and −0.02 ± 0.56 respectively, p = 0.048). However, dietary PRAL scores fell significantly in both dietary groups during the 7-day trial. Since low dietary PRAL scores have been related to improve metabolic parameters, adoption of a vegan diets for several days per week should be explored as a diet strategy to lower disease risk.

KW - Potential renal acid load

KW - Urine pH

KW - Vegan diets

UR - http://www.scopus.com/inward/record.url?scp=85021809776&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85021809776&partnerID=8YFLogxK

U2 - 10.1007/s11130-017-0620-7

DO - 10.1007/s11130-017-0620-7

M3 - Article

SP - 1

EP - 6

JO - Plant Foods for Human Nutrition

JF - Plant Foods for Human Nutrition

SN - 0921-9668

ER -