Evidence of ancient papillomavirus recombination

Arvind Varsani, Eric van der Walt, Livio Heath, Edward P. Rybicki, Anna Lise Williamson, Darren P. Martin

Research output: Contribution to journalArticle

53 Citations (Scopus)

Abstract

An open question amongst papillomavirus taxonomists is whether recombination has featured in the evolutionary history of these viruses. Since the onset of the global AIDS epidemic, the question is somewhat less academic, because immune-compromised human immunodeficiency virus patients are often co-infected with extraordinarily diverse mixtures of human papillomavirus (HPV) types. It is expected that these conditions may facilitate the emergence of HPV recombinants, some of which might have novel pathogenic properties. Here, a range of rigorous analyses is applied to full-genome sequences of papillomaviruses to provide convincing statistical and phylogenetic evidence that evolutionarily relevant papillomavirus recombination can occur.

Original languageEnglish (US)
Pages (from-to)2527-2531
Number of pages5
JournalJournal of General Virology
Volume87
Issue number9
DOIs
StatePublished - Sep 2006
Externally publishedYes

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Genetic Recombination
Acquired Immunodeficiency Syndrome
History
HIV
Genome
Viruses

ASJC Scopus subject areas

  • Virology
  • Immunology

Cite this

Varsani, A., van der Walt, E., Heath, L., Rybicki, E. P., Williamson, A. L., & Martin, D. P. (2006). Evidence of ancient papillomavirus recombination. Journal of General Virology, 87(9), 2527-2531. https://doi.org/10.1099/vir.0.81917-0

Evidence of ancient papillomavirus recombination. / Varsani, Arvind; van der Walt, Eric; Heath, Livio; Rybicki, Edward P.; Williamson, Anna Lise; Martin, Darren P.

In: Journal of General Virology, Vol. 87, No. 9, 09.2006, p. 2527-2531.

Research output: Contribution to journalArticle

Varsani, A, van der Walt, E, Heath, L, Rybicki, EP, Williamson, AL & Martin, DP 2006, 'Evidence of ancient papillomavirus recombination', Journal of General Virology, vol. 87, no. 9, pp. 2527-2531. https://doi.org/10.1099/vir.0.81917-0
Varsani A, van der Walt E, Heath L, Rybicki EP, Williamson AL, Martin DP. Evidence of ancient papillomavirus recombination. Journal of General Virology. 2006 Sep;87(9):2527-2531. https://doi.org/10.1099/vir.0.81917-0
Varsani, Arvind ; van der Walt, Eric ; Heath, Livio ; Rybicki, Edward P. ; Williamson, Anna Lise ; Martin, Darren P. / Evidence of ancient papillomavirus recombination. In: Journal of General Virology. 2006 ; Vol. 87, No. 9. pp. 2527-2531.
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