Epileptic seizures: Quakes of the brain?

Ivan Osorio, Mark G. Frei, Didier Sornette, John Milton, Ying-Cheng Lai

Research output: Contribution to journalArticle

64 Scopus citations

Abstract

A dynamical analogy supported by five scale-free statistics (the Gutenberg-Richter distribution of event sizes, the distribution of interevent intervals, the Omori and inverse Omori laws, and the conditional waiting time until the next event) is shown to exist between two classes of seizures ("focal" in humans and generalized in animals) and earthquakes. Increments in excitatory interneuronal coupling in animals expose the system's dependence on this parameter and its dynamical transmutability: moderate increases lead to power-law behavior of seizure energy and interevent times, while marked ones to scale-free (power-law) coextensive with characteristic scales and events. The coextensivity of power law and characteristic size regimes is predicted by models of coupled heterogeneous threshold oscillators of relaxation and underscores the role of coupling strength in shaping the dynamics of these systems.

Original languageEnglish (US)
Article number021919
JournalPhysical Review E - Statistical, Nonlinear, and Soft Matter Physics
Volume82
Issue number2
DOIs
StatePublished - Aug 20 2010

ASJC Scopus subject areas

  • Statistical and Nonlinear Physics
  • Statistics and Probability
  • Condensed Matter Physics

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