Encapsulation of gold nanoparticles in a DNA origami cage

Zhao Zhao; Erica L. Jacovetty; Yan Liu; Hao Yan

doi:10.1002/anie.201006818

Encapsulation of gold nanoparticles in a DNA origami cage

Zhao Zhao, Erica L. Jacovetty, Yan Liu, Hao Yan

Research output: Contribution to journal › Article › peer-review

130 Scopus citations

Abstract

Fold and label: A critical challenge in nanoparticle (NP) surface functionalization is to label the NP surface with a single copy of a functional group or to display multiple, unique molecules on the NP surface with control of the orientation and intermolecular distance. This challenge was addressed with the construction of a spatially addressable, self-assembling DNA origami nanocage that encapsulates gold nanoparticles and interrupts its surface symmetry (see scheme).

Original language	English (US)
Pages (from-to)	2041-2044
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	50
Issue number	9
DOIs	https://doi.org/10.1002/anie.201006818
State	Published - Feb 25 2011

Keywords

DNA
gold
nanoparticles
nanotechnology

ASJC Scopus subject areas

Catalysis
General Chemistry

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10.1002/anie.201006818

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AU - Liu, Yan

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Encapsulation of gold nanoparticles in a DNA origami cage

Abstract

Keywords

ASJC Scopus subject areas

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