Design, synthesis, and functionalization of nanomaterials for therapeutic drug delivery

Taraka Sai Pavan Grandhi; Kaushal Rege

doi:10.1007/978-94-017-8739-0_9

Design, synthesis, and functionalization of nanomaterials for therapeutic drug delivery

Taraka Sai Pavan Grandhi, Kaushal Rege

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Nanomaterials have the potential to solve some of the toughest challenges facing modern medicine. Their unique optical, magnetic and chemical properties at the nanoscale make them different from their macroscale counterparts. Successful application of nanomaterials can revolutionize therapeutics, diagnostics and imaging in several biomedical applications. Selfassembled amphiphilic polymeric nanoparticles have been employed to carry poorly soluble chemotherapeutic drugs. Loading of anticancer chemotherapeutic drugs into self assembled polymeric nanoparticles have shown to increase their circulation time, tumor localization and therapeutic potential. This book chapter provides an introductory discussion to organic nanotechnologies for drug delivery. Promising advances in the field of nanomedicine will be discussed and an outlook to the future will be provided.

Original language	English (US)
Pages (from-to)	157-182
Number of pages	26
Journal	Advances in experimental medicine and biology
Volume	811
DOIs	https://doi.org/10.1007/978-94-017-8739-0_9
State	Published - 2014

Keywords

Cancer
Drug-delivery
FDA
Liposomes
Micelles
Multifunctional nanomedicine
PLGAnanoparticles

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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10.1007/978-94-017-8739-0_9

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abstract = "Nanomaterials have the potential to solve some of the toughest challenges facing modern medicine. Their unique optical, magnetic and chemical properties at the nanoscale make them different from their macroscale counterparts. Successful application of nanomaterials can revolutionize therapeutics, diagnostics and imaging in several biomedical applications. Selfassembled amphiphilic polymeric nanoparticles have been employed to carry poorly soluble chemotherapeutic drugs. Loading of anticancer chemotherapeutic drugs into self assembled polymeric nanoparticles have shown to increase their circulation time, tumor localization and therapeutic potential. This book chapter provides an introductory discussion to organic nanotechnologies for drug delivery. Promising advances in the field of nanomedicine will be discussed and an outlook to the future will be provided.",

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Design, synthesis, and functionalization of nanomaterials for therapeutic drug delivery

Abstract

Keywords

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