Delivery of TRAIL-expressing plasmid DNA to cancer cells: In vitro and in vivo using aminoglycoside-derived polymers

Engineering & Materials Science

• Aminoglycosides 100%
• Cell death 73%
• DNA 51%
• Cells 48%
• Polymers 36%
• Tumors 25%
• Ligands 22%
• Tumor Necrosis Factor-alpha 15%
• Fibroblasts 12%
• Toxicity 9%
• Proteins 7%

Medicine & Life Sciences

• Aminoglycosides 55%
• Polymers 44%
• Plasmids 40%
• DNA 27%
• In Vitro Techniques 21%
• Neoplasms 16%
• Cell Death 14%
• Apoptosis 11%
• Paromomycin 9%
• TNF-Related Apoptosis-Inducing Ligand 9%
• Ligands 8%
• TNF-Related Apoptosis-Inducing Ligand Receptors 8%
• Death Domain Receptors 7%
• Caspase 8 7%
• Caspases 6%
• Transgenes 6%
• HeLa Cells 6%
• Urinary Bladder Neoplasms 5%
• Tumor Burden 5%
• Uterine Cervical Neoplasms 5%
• Cause of Death 4%
• Fibroblasts 4%
• Tumor Necrosis Factor-alpha 4%
• Western Blotting 4%
• Survival 3%
• Growth 3%

Chemical Compounds

• Cell Death 53%
• Ligand 14%
• Reduction 7%
• Amount 7%
• Protein 6%