Abstract
Secretion of digestive enzymes by the exocrine pancreas is thought to be initiated by a rise in cytosol Ca2+ activity. It is not yet clear whether influx of extracellular calcium or release of calcium from an intracellular site is responsible for this event. Review of the literature provides evidence that both extracellular and intracellular calcium regulate secretion and that under different circumstances each may be an important source of 'messenger' calcium.
Original language | English (US) |
---|---|
Pages (from-to) | 323-333 |
Number of pages | 11 |
Journal | Life Sciences |
Volume | 23 |
Issue number | 4 |
DOIs | |
State | Published - Jul 24 1978 |
Externally published | Yes |
ASJC Scopus subject areas
- General Pharmacology, Toxicology and Pharmaceutics
- General Biochemistry, Genetics and Molecular Biology