Abstract

Pyridine and its heterocyclic derivatives are widely encountered in industrial wastewaters, and they are relatively recalcitrant to biodegradation. Pyridine biodegradation is initiated by two mono-oxygenation reactions that compete for intracellular electron donor (2H). In our experiments, UV photolysis of pyridine generated succinate, whose oxidation augmented the intracellular electron donor and accelerated pyridine biodegradation and mineralization. The first mono-oxygenation reaction always was faster than the second one, because electrons provided by intracellular electron donors were preferentially utilized by the first mono-oxygenase; this was true even when the concentration of 2HP was greater than the concentration of pyridine. In addition, the first mono-oxygenation had faster kinetics because it had higher affinity for its substrate (pyridine), along with less substrate self-inhibition.

Original languageEnglish (US)
Pages (from-to)1-9
Number of pages9
JournalBiodegradation
DOIs
StateAccepted/In press - May 21 2018

Fingerprint

Oxygenation
oxygenation
Pyridine
Electrons
electron
biodegradation
Biodegradation
substrate
photolysis
Oxygenases
Photolysis
Succinic Acid
Substrates
mineralization
Waste Water
wastewater
oxidation
kinetics
pyridine
2-hydroxypyridine

Keywords

  • 2-Hydroxypyridine
  • Competition for electrons
  • Mono-oxygenation
  • Pyridine

ASJC Scopus subject areas

  • Environmental Engineering
  • Microbiology
  • Bioengineering
  • Environmental Chemistry
  • Pollution

Cite this

Competition for electrons between mono-oxygenations of pyridine and 2-hydroxypyridine. / Yang, Chao; Tang, Yingxia; Xu, Hua; Yan, Ning; Li, Naiyu; Zhang, Yongming; Rittmann, Bruce.

In: Biodegradation, 21.05.2018, p. 1-9.

Research output: Contribution to journalArticle

Yang, Chao ; Tang, Yingxia ; Xu, Hua ; Yan, Ning ; Li, Naiyu ; Zhang, Yongming ; Rittmann, Bruce. / Competition for electrons between mono-oxygenations of pyridine and 2-hydroxypyridine. In: Biodegradation. 2018 ; pp. 1-9.
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AU - Yang, Chao

AU - Tang, Yingxia

AU - Xu, Hua

AU - Yan, Ning

AU - Li, Naiyu

AU - Zhang, Yongming

AU - Rittmann, Bruce

PY - 2018/5/21

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N2 - Pyridine and its heterocyclic derivatives are widely encountered in industrial wastewaters, and they are relatively recalcitrant to biodegradation. Pyridine biodegradation is initiated by two mono-oxygenation reactions that compete for intracellular electron donor (2H). In our experiments, UV photolysis of pyridine generated succinate, whose oxidation augmented the intracellular electron donor and accelerated pyridine biodegradation and mineralization. The first mono-oxygenation reaction always was faster than the second one, because electrons provided by intracellular electron donors were preferentially utilized by the first mono-oxygenase; this was true even when the concentration of 2HP was greater than the concentration of pyridine. In addition, the first mono-oxygenation had faster kinetics because it had higher affinity for its substrate (pyridine), along with less substrate self-inhibition.

AB - Pyridine and its heterocyclic derivatives are widely encountered in industrial wastewaters, and they are relatively recalcitrant to biodegradation. Pyridine biodegradation is initiated by two mono-oxygenation reactions that compete for intracellular electron donor (2H). In our experiments, UV photolysis of pyridine generated succinate, whose oxidation augmented the intracellular electron donor and accelerated pyridine biodegradation and mineralization. The first mono-oxygenation reaction always was faster than the second one, because electrons provided by intracellular electron donors were preferentially utilized by the first mono-oxygenase; this was true even when the concentration of 2HP was greater than the concentration of pyridine. In addition, the first mono-oxygenation had faster kinetics because it had higher affinity for its substrate (pyridine), along with less substrate self-inhibition.

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