Comparative pathogenesis of haemorrhagic enteritis virus (HEV) infection in turkeys and chickens

S. Rautenschlein, M. Suresh, U. Neumann, J. M. Sharma

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

The pathogenesis of haemorrhagic enteritis virus (HEV) infection in chickens 3-4 days post-infection was compared with that in turkeys. As expected, infected turkeys showed HEV-specific lesions that included enlargement and mottling of the spleen, as well as haemorrhagic enteritis. In infected chickens, only splenomegaly was observed. The number of HEV-infected cells in the spleen was significantly (P < 0.05) higher in the turkey than in the chicken. In both species, the immunohistochemical labelling of B-cell surface determinants was diminished and the splenic B-cell areas were undetectable after HEV infection. Infection with HEV resulted in an increase in nitric oxide production by macrophages in chickens but not in turkeys.

Original languageEnglish (US)
Pages (from-to)251-261
Number of pages11
JournalJournal of Comparative Pathology
Volume119
Issue number3
StatePublished - 1998
Externally publishedYes

Fingerprint

Aviadenovirus
Enteritis
Virus Diseases
Chickens
pathogenesis
chickens
infection
B-lymphocytes
Viruses
hemorrhagic enteritis
B-Lymphocytes
Spleen
splenomegaly
splenocytes
lesions (animal)
Splenomegaly
nitric oxide
Infection
spleen
macrophages

ASJC Scopus subject areas

  • Animal Science and Zoology

Cite this

Rautenschlein, S., Suresh, M., Neumann, U., & Sharma, J. M. (1998). Comparative pathogenesis of haemorrhagic enteritis virus (HEV) infection in turkeys and chickens. Journal of Comparative Pathology, 119(3), 251-261.

Comparative pathogenesis of haemorrhagic enteritis virus (HEV) infection in turkeys and chickens. / Rautenschlein, S.; Suresh, M.; Neumann, U.; Sharma, J. M.

In: Journal of Comparative Pathology, Vol. 119, No. 3, 1998, p. 251-261.

Research output: Contribution to journalArticle

Rautenschlein, S, Suresh, M, Neumann, U & Sharma, JM 1998, 'Comparative pathogenesis of haemorrhagic enteritis virus (HEV) infection in turkeys and chickens', Journal of Comparative Pathology, vol. 119, no. 3, pp. 251-261.
Rautenschlein, S. ; Suresh, M. ; Neumann, U. ; Sharma, J. M. / Comparative pathogenesis of haemorrhagic enteritis virus (HEV) infection in turkeys and chickens. In: Journal of Comparative Pathology. 1998 ; Vol. 119, No. 3. pp. 251-261.
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