Cognitive contributions to freezing of gait in parkinson disease

Implications for physical rehabilitation

Daniel Peterson, Laurie A. King, Rajal G. Cohen, Fay B. Horak

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

People with Parkinson disease (PD) who show freezing of gait also have dysfunction in cognitive domains that interact with mobility. Specifically, freezing of gait is associated with executive dysfunction involving response inhibition, divided attention or switching attention, and visuospatial function. The neural control impairments leading to freezing of gait have recently been attributed to higher-level, executive and attentional cortical processes involved in coordinating posture and gait rather than to lower-level, sensorimotor impairments. To date, rehabilitation for freezing of gait primarily has focused on compensatory mobility training to overcome freezing events, such as sensory cueing and voluntary step planning. Recently, a few interventions have focused on restitutive, rather than compensatory, therapy. Given the documented impairments in executive function specific to patients with PD who freeze and increasing evidence of overlap between cognitive and motor function, incorporating cognitive challenges with mobility training may have important benefits for patients with freezing of gait. Thus, a novel theoretical framework is proposed for exercise interventions that jointly address both the specific cognitive and mobility challenges of people with PD who freeze.

Original languageEnglish (US)
Pages (from-to)659-670
Number of pages12
JournalPhysical Therapy
Volume96
Issue number5
DOIs
StatePublished - May 1 2016
Externally publishedYes

Fingerprint

Gait
Freezing
Parkinson Disease
Rehabilitation
Executive Function
Posture
Cognition
Exercise

ASJC Scopus subject areas

  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

Cognitive contributions to freezing of gait in parkinson disease : Implications for physical rehabilitation. / Peterson, Daniel; King, Laurie A.; Cohen, Rajal G.; Horak, Fay B.

In: Physical Therapy, Vol. 96, No. 5, 01.05.2016, p. 659-670.

Research output: Contribution to journalArticle

Peterson, Daniel ; King, Laurie A. ; Cohen, Rajal G. ; Horak, Fay B. / Cognitive contributions to freezing of gait in parkinson disease : Implications for physical rehabilitation. In: Physical Therapy. 2016 ; Vol. 96, No. 5. pp. 659-670.
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