Characterization and use of the spent beam for serial operation of LCLS

Sébastien Boutet, Lutz Foucar, Thomas R.M. Barends, Sabine Botha, R. Bruce Doak, Jason E. Koglin, Marc Messerschmidt, Karol Nass, Ilme Schlichting, M. Marvin Seibert, Robert L. Shoeman, Garth J. Williams

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

X-ray free-electron laser sources such as the Linac Coherent Light Source offer very exciting possibilities for unique research. However, beam time at such facilities is very limited and in high demand. This has led to significant efforts towards beam multiplexing of various forms. One such effort involves re-using the so-called spent beam that passes through the hole in an area detector after a weak interaction with a primary sample. This beam can be refocused into a secondary interaction region and used for a second, independent experiment operating in series. The beam profile of this refocused beam was characterized for a particular experimental geometry at the Coherent X-ray Imaging instrument at LCLS. A demonstration of this multiplexing capability was performed with two simultaneous serial femtosecond crystallography experiments, both yielding interpretable data of sufficient quality to produce electron density maps.

Original languageEnglish (US)
Pages (from-to)634-643
Number of pages10
JournalJournal of Synchrotron Radiation
Volume22
DOIs
StatePublished - Jan 1 2015
Externally publishedYes

Fingerprint

Multiplexing
Light sources
X ray lasers
Crystallography
Free electron lasers
Carrier concentration
Demonstrations
Experiments
Detectors
multiplexing
Imaging techniques
X rays
Geometry
coherent light
free electron lasers
crystallography
light sources
x rays
detectors
profiles

Keywords

  • FEL
  • multiplexing
  • nanocrystallography Special issue on X-ray Free-Electron Lasers
  • serial femtosecond crystallography
  • SFX
  • X-ray

ASJC Scopus subject areas

  • Radiation
  • Nuclear and High Energy Physics
  • Instrumentation

Cite this

Boutet, S., Foucar, L., Barends, T. R. M., Botha, S., Doak, R. B., Koglin, J. E., ... Williams, G. J. (2015). Characterization and use of the spent beam for serial operation of LCLS. Journal of Synchrotron Radiation, 22, 634-643. https://doi.org/10.1107/S1600577515004002

Characterization and use of the spent beam for serial operation of LCLS. / Boutet, Sébastien; Foucar, Lutz; Barends, Thomas R.M.; Botha, Sabine; Doak, R. Bruce; Koglin, Jason E.; Messerschmidt, Marc; Nass, Karol; Schlichting, Ilme; Seibert, M. Marvin; Shoeman, Robert L.; Williams, Garth J.

In: Journal of Synchrotron Radiation, Vol. 22, 01.01.2015, p. 634-643.

Research output: Contribution to journalArticle

Boutet, S, Foucar, L, Barends, TRM, Botha, S, Doak, RB, Koglin, JE, Messerschmidt, M, Nass, K, Schlichting, I, Seibert, MM, Shoeman, RL & Williams, GJ 2015, 'Characterization and use of the spent beam for serial operation of LCLS', Journal of Synchrotron Radiation, vol. 22, pp. 634-643. https://doi.org/10.1107/S1600577515004002
Boutet, Sébastien ; Foucar, Lutz ; Barends, Thomas R.M. ; Botha, Sabine ; Doak, R. Bruce ; Koglin, Jason E. ; Messerschmidt, Marc ; Nass, Karol ; Schlichting, Ilme ; Seibert, M. Marvin ; Shoeman, Robert L. ; Williams, Garth J. / Characterization and use of the spent beam for serial operation of LCLS. In: Journal of Synchrotron Radiation. 2015 ; Vol. 22. pp. 634-643.
@article{e0f554fa309048a5bfa6355ffea298d9,
title = "Characterization and use of the spent beam for serial operation of LCLS",
abstract = "X-ray free-electron laser sources such as the Linac Coherent Light Source offer very exciting possibilities for unique research. However, beam time at such facilities is very limited and in high demand. This has led to significant efforts towards beam multiplexing of various forms. One such effort involves re-using the so-called spent beam that passes through the hole in an area detector after a weak interaction with a primary sample. This beam can be refocused into a secondary interaction region and used for a second, independent experiment operating in series. The beam profile of this refocused beam was characterized for a particular experimental geometry at the Coherent X-ray Imaging instrument at LCLS. A demonstration of this multiplexing capability was performed with two simultaneous serial femtosecond crystallography experiments, both yielding interpretable data of sufficient quality to produce electron density maps.",
keywords = "FEL, multiplexing, nanocrystallography Special issue on X-ray Free-Electron Lasers, serial femtosecond crystallography, SFX, X-ray",
author = "S{\'e}bastien Boutet and Lutz Foucar and Barends, {Thomas R.M.} and Sabine Botha and Doak, {R. Bruce} and Koglin, {Jason E.} and Marc Messerschmidt and Karol Nass and Ilme Schlichting and Seibert, {M. Marvin} and Shoeman, {Robert L.} and Williams, {Garth J.}",
year = "2015",
month = "1",
day = "1",
doi = "10.1107/S1600577515004002",
language = "English (US)",
volume = "22",
pages = "634--643",
journal = "Journal of Synchrotron Radiation",
issn = "0909-0495",
publisher = "International Union of Crystallography",

}

TY - JOUR

T1 - Characterization and use of the spent beam for serial operation of LCLS

AU - Boutet, Sébastien

AU - Foucar, Lutz

AU - Barends, Thomas R.M.

AU - Botha, Sabine

AU - Doak, R. Bruce

AU - Koglin, Jason E.

AU - Messerschmidt, Marc

AU - Nass, Karol

AU - Schlichting, Ilme

AU - Seibert, M. Marvin

AU - Shoeman, Robert L.

AU - Williams, Garth J.

PY - 2015/1/1

Y1 - 2015/1/1

N2 - X-ray free-electron laser sources such as the Linac Coherent Light Source offer very exciting possibilities for unique research. However, beam time at such facilities is very limited and in high demand. This has led to significant efforts towards beam multiplexing of various forms. One such effort involves re-using the so-called spent beam that passes through the hole in an area detector after a weak interaction with a primary sample. This beam can be refocused into a secondary interaction region and used for a second, independent experiment operating in series. The beam profile of this refocused beam was characterized for a particular experimental geometry at the Coherent X-ray Imaging instrument at LCLS. A demonstration of this multiplexing capability was performed with two simultaneous serial femtosecond crystallography experiments, both yielding interpretable data of sufficient quality to produce electron density maps.

AB - X-ray free-electron laser sources such as the Linac Coherent Light Source offer very exciting possibilities for unique research. However, beam time at such facilities is very limited and in high demand. This has led to significant efforts towards beam multiplexing of various forms. One such effort involves re-using the so-called spent beam that passes through the hole in an area detector after a weak interaction with a primary sample. This beam can be refocused into a secondary interaction region and used for a second, independent experiment operating in series. The beam profile of this refocused beam was characterized for a particular experimental geometry at the Coherent X-ray Imaging instrument at LCLS. A demonstration of this multiplexing capability was performed with two simultaneous serial femtosecond crystallography experiments, both yielding interpretable data of sufficient quality to produce electron density maps.

KW - FEL

KW - multiplexing

KW - nanocrystallography Special issue on X-ray Free-Electron Lasers

KW - serial femtosecond crystallography

KW - SFX

KW - X-ray

UR - http://www.scopus.com/inward/record.url?scp=84929500960&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84929500960&partnerID=8YFLogxK

U2 - 10.1107/S1600577515004002

DO - 10.1107/S1600577515004002

M3 - Article

AN - SCOPUS:84929500960

VL - 22

SP - 634

EP - 643

JO - Journal of Synchrotron Radiation

JF - Journal of Synchrotron Radiation

SN - 0909-0495

ER -