Cardiovascular disease in diabetes mellitus type 2: A potential role for novel cardiovascular risk factors

John M. Hayden, Peter D. Reaven

Research output: Contribution to journalReview article

100 Scopus citations

Abstract

A major consequence of diabetes mellitus type 2 is the accelerated development of atherosclerosis. Assessment of conventional risk factors such as plasma lipids, lipoproteins and hypertension only partly account for the excessive risk of developing cardiovascular disease in this population. Increasing evidence has emerged suggesting that conditions associated with diabetes mellitus type 2, such as insulin resistance, hyperinsulinemia and hyperglycemia, may also play a significant role in regulating 'novel' cardiovascular risk factors. These factors and their potential roles in the development of atherosclerosis and cardiovascular events are discussed in this review. (C) 2000 Lippincott Williams and Wilkins.

Original languageEnglish (US)
Pages (from-to)519-528
Number of pages10
JournalCurrent Opinion in Lipidology
Volume11
Issue number5
DOIs
StatePublished - Oct 23 2000
Externally publishedYes

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Molecular Biology
  • Genetics
  • Nutrition and Dietetics
  • Cardiology and Cardiovascular Medicine
  • Cell Biology

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