Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I

Y. H. Hsiang, R. Hertzberg, Sidney Hecht, L. F. Liu

Research output: Contribution to journalArticle

2002 Citations (Scopus)
Original languageEnglish (US)
Pages (from-to)14873-14878
Number of pages6
JournalJournal of Biological Chemistry
Volume260
Issue number27
StatePublished - 1985
Externally publishedYes

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Camptothecin
Biological Models
Type II DNA Topoisomerase
Type I DNA Topoisomerase
DNA Breaks
Single-Stranded DNA
HeLa Cells
Protein Binding
Thymus Gland
Animals
Plasmids
Binding Sites
Kinetics
DNA
Proteins

ASJC Scopus subject areas

  • Biochemistry

Cite this

Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I. / Hsiang, Y. H.; Hertzberg, R.; Hecht, Sidney; Liu, L. F.

In: Journal of Biological Chemistry, Vol. 260, No. 27, 1985, p. 14873-14878.

Research output: Contribution to journalArticle

Hsiang, YH, Hertzberg, R, Hecht, S & Liu, LF 1985, 'Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I', Journal of Biological Chemistry, vol. 260, no. 27, pp. 14873-14878.
Hsiang, Y. H. ; Hertzberg, R. ; Hecht, Sidney ; Liu, L. F. / Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I. In: Journal of Biological Chemistry. 1985 ; Vol. 260, No. 27. pp. 14873-14878.
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