Administration of small doses of apomorphine attenuates feeding in non-deprived pigeons

Research output: Contribution to journalArticle

18 Scopus citations

Abstract

The dopamine agonist apomorphine was administered peripherally at small doses of 25, 50 or 100 μg to non-deprived pigeons, either in the morning or in the afternoon. The food and water consumption of the birds was then measured at 4 times (30, 60, 90 and 120 min) after the injection. In the control condition (injection of saline), the pigeons ate less in the morning than in the afternoon, whereas a reverse situation was observed for drinking. Administration of apomorphine attenuated the food consumption in a dose-related fashion, at both times of the day, and for no longer than 90 min post-injection; the reduction of feeding was relatively larger when the drug was given in the morning than in the afternoon, and it was not accompanied by consistent changes of the water consumption. These results show that in pigeons, the feeding-like responses to apomorphine treatment (pecking, swallowing, mandibulating) which have been described previously are not associated with an actual enhancement of the food intake. Possible mechanisms and loci of action of dopamine agonists on these 2 types of behaviors are discussed.

Original languageEnglish (US)
Pages (from-to)581-585
Number of pages5
JournalPhysiology and Behavior
Volume33
Issue number4
DOIs
StatePublished - Oct 1984
Externally publishedYes

Keywords

  • Apomorphine
  • Dopamine
  • Dopamine agonists
  • Food intake
  • Pecking
  • Pigeons
  • Stereotypy
  • Water intake

ASJC Scopus subject areas

  • Experimental and Cognitive Psychology
  • Behavioral Neuroscience

Fingerprint Dive into the research topics of 'Administration of small doses of apomorphine attenuates feeding in non-deprived pigeons'. Together they form a unique fingerprint.

  • Cite this