A feedback control systems view of epileptic seizures

Konstantinos Tsakalis; N. Chakravarthy; Sh Sabesan; L. D. Iasemidis; P. M. Pardalos

doi:10.1007/s10559-006-0087-2

A feedback control systems view of epileptic seizures

Konstantinos Tsakalis, N. Chakravarthy, Sh Sabesan, L. D. Iasemidis, P. M. Pardalos

Electrical Engineering

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

Abstract

To understand basic functional mechanisms that cause epileptic seizures, the paper discusses some key features of theoretical brain functioning models. The hypothesis is put forward that a plausible reason for seizures is pathological feedback in brain circuitry. The analysis of such circuitry has an interesting physical interpretation and may be used to cure epilepsy.

Original language	English (US)
Pages (from-to)	483-495
Number of pages	13
Journal	Cybernetics and Systems Analysis
Volume	42
Issue number	4
DOIs	https://doi.org/10.1007/s10559-006-0087-2
State	Published - Jul 2006

Keywords

Coupled-oscillator model
Epileptic seizure
Feedback control system

ASJC Scopus subject areas

General Computer Science

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10.1007/s10559-006-0087-2

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title = "A feedback control systems view of epileptic seizures",

abstract = "To understand basic functional mechanisms that cause epileptic seizures, the paper discusses some key features of theoretical brain functioning models. The hypothesis is put forward that a plausible reason for seizures is pathological feedback in brain circuitry. The analysis of such circuitry has an interesting physical interpretation and may be used to cure epilepsy.",

keywords = "Coupled-oscillator model, Epileptic seizure, Feedback control system",

author = "Konstantinos Tsakalis and N. Chakravarthy and Sh Sabesan and Iasemidis, {L. D.} and Pardalos, {P. M.}",

note = "Funding Information: This research is supported by the American Epilepsy Research Foundation and the Ali Paris Fund for LKS Research and Education, and National Institutes of Health (R01NS396871). Professor Pardalos{\textquoteright} research was partially supported by NIH and CRDF grants.",

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AU - Sabesan, Sh

AU - Iasemidis, L. D.

AU - Pardalos, P. M.

N1 - Funding Information: This research is supported by the American Epilepsy Research Foundation and the Ali Paris Fund for LKS Research and Education, and National Institutes of Health (R01NS396871). Professor Pardalos’ research was partially supported by NIH and CRDF grants.

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N2 - To understand basic functional mechanisms that cause epileptic seizures, the paper discusses some key features of theoretical brain functioning models. The hypothesis is put forward that a plausible reason for seizures is pathological feedback in brain circuitry. The analysis of such circuitry has an interesting physical interpretation and may be used to cure epilepsy.

AB - To understand basic functional mechanisms that cause epileptic seizures, the paper discusses some key features of theoretical brain functioning models. The hypothesis is put forward that a plausible reason for seizures is pathological feedback in brain circuitry. The analysis of such circuitry has an interesting physical interpretation and may be used to cure epilepsy.

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KW - Feedback control system

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A feedback control systems view of epileptic seizures

Abstract

Keywords

ASJC Scopus subject areas

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